WEBVTT

1
00:00:00.480 --> 00:00:04.320
This may be the most controversial thing we have on this table.

2
00:00:04.320 --> 00:00:07.680
This is a peptide that absolutely torches belly fat

3
00:00:07.680 --> 00:00:09.120
at a disproportionate rate.

4
00:00:09.120 --> 00:00:10.880
And what we found is not only do patients lose

5
00:00:10.880 --> 00:00:12.440
an incredible amount of weight,

6
00:00:12.440 --> 00:00:14.520
but they also get the best improvements

7
00:00:14.520 --> 00:00:15.760
we've ever seen in their liver health.

8
00:00:15.760 --> 00:00:16.920
It's absolutely wild.

9
00:00:16.920 --> 00:00:20.480
And I think this is going to be a trillion dollar rug

10
00:00:20.480 --> 00:00:21.560
when it comes out.

11
00:00:21.560 --> 00:00:22.920
And I'm probably here because you were an expert

12
00:00:22.920 --> 00:00:24.200
in this subject matter, and it's worth saying

13
00:00:24.200 --> 00:00:26.360
that there was some significant news about this.

14
00:00:26.360 --> 00:00:27.200
Correct.

15
00:00:27.200 --> 00:00:30.440
FDA saying that in July, they are going to consider

16
00:00:30.440 --> 00:00:32.200
legalize it, seven peptides.

17
00:00:32.200 --> 00:00:34.960
And by farm as estimate, it might be the most dangerous thing

18
00:00:34.960 --> 00:00:36.480
to their entire business model.

19
00:00:36.480 --> 00:00:38.520
So do you think it is plausible?

20
00:00:38.520 --> 00:00:40.960
That big farmer didn't want these in the hands

21
00:00:40.960 --> 00:00:43.200
of regular people because they can't patent this

22
00:00:43.200 --> 00:00:44.120
and it's powerful.

23
00:00:44.120 --> 00:00:45.480
110%.

24
00:00:45.480 --> 00:00:47.720
Because the question isn't, what can peptides do?

25
00:00:47.720 --> 00:00:49.320
It's what can't they do?

26
00:00:49.320 --> 00:00:51.520
And we've got several peptides here in front of us.

27
00:00:51.520 --> 00:00:52.960
We want to go through all of them.

28
00:00:52.960 --> 00:00:53.960
Let's do it.

29
00:00:53.960 --> 00:00:57.160
So this is probably the most well-known peptide

30
00:00:57.160 --> 00:00:59.680
for skin complexion, and it improves quality of hair

31
00:00:59.680 --> 00:01:00.360
and nails.

32
00:01:00.360 --> 00:01:02.560
And then epithelan is maybe, maybe not

33
00:01:02.560 --> 00:01:04.040
going to be the fountain of youth.

34
00:01:04.040 --> 00:01:06.080
But I'm very skeptical as far as that goes.

35
00:01:06.080 --> 00:01:07.600
Next, we've got this.

36
00:01:07.600 --> 00:01:09.560
If you injected that at night, it would improve

37
00:01:09.560 --> 00:01:10.600
your quality of your sleep.

38
00:01:10.600 --> 00:01:12.000
Next, Molana Tan, too.

39
00:01:12.000 --> 00:01:14.680
And this will actually end up giving you a deep tan

40
00:01:14.680 --> 00:01:17.280
in response to just a little bit of UV sun exposure.

41
00:01:17.280 --> 00:01:19.120
It will also give you some of the most impressive

42
00:01:19.120 --> 00:01:20.320
erections you've ever had in your life.

43
00:01:20.320 --> 00:01:21.400
So be warned.

44
00:01:21.400 --> 00:01:22.320
And what else have we got?

45
00:01:22.320 --> 00:01:23.160
Oh my gosh.

46
00:01:23.200 --> 00:01:24.480
Medley and blue, where people take it

47
00:01:24.480 --> 00:01:25.920
and they think it's going to make a live forever.

48
00:01:25.920 --> 00:01:26.680
Don't take this.

49
00:01:26.680 --> 00:01:29.200
It literally will stain your nails blue and your hair blue.

50
00:01:29.200 --> 00:01:31.320
These two here stimulate building muscle.

51
00:01:31.320 --> 00:01:33.760
This one can aid with healing after an injury.

52
00:01:33.760 --> 00:01:36.000
And then is this, this, this, this.

53
00:01:36.000 --> 00:01:36.760
It's crazy.

54
00:01:36.760 --> 00:01:37.480
It's wild.

55
00:01:37.480 --> 00:01:38.400
So why don't I take it?

56
00:01:38.400 --> 00:01:39.960
Well, we need to talk about that.

57
00:01:39.960 --> 00:01:41.160
Because they're trade-offs.

58
00:01:41.160 --> 00:01:43.280
But also outside of the world of peptides for a second,

59
00:01:43.280 --> 00:01:45.080
I've got these three vials.

60
00:01:45.080 --> 00:01:45.760
Do you know what those are?

61
00:01:45.760 --> 00:01:49.040
Yeah, this is, unfortunately, our future for not careful.

62
00:01:49.040 --> 00:01:49.560
Explain.

63
00:01:49.560 --> 00:01:51.800
So what we've got here is representing

64
00:01:51.800 --> 00:01:55.440
the fertility trajectory for young men.

65
00:01:55.440 --> 00:01:56.160
I'm so scared.

66
00:01:57.880 --> 00:02:00.360
Guys, I've got a favor to ask before this episode begins.

67
00:02:00.360 --> 00:02:02.600
The algorithm, if you follow a show,

68
00:02:02.600 --> 00:02:05.160
deliver you the best episodes from that show

69
00:02:05.160 --> 00:02:06.760
very prominently in your feed.

70
00:02:06.760 --> 00:02:08.880
So when we have our best episodes on this show,

71
00:02:08.880 --> 00:02:10.960
the most shared episodes, the most rated episodes,

72
00:02:10.960 --> 00:02:12.160
I would love you to know.

73
00:02:12.160 --> 00:02:13.840
And the simple way for you to know that

74
00:02:13.840 --> 00:02:15.160
is to hit that follow button.

75
00:02:15.160 --> 00:02:17.440
But also, it's the simple, easy,

76
00:02:17.440 --> 00:02:19.680
free thing that you can do to help us make the show better.

77
00:02:19.680 --> 00:02:22.280
I would be hugely grateful if you could take a minute

78
00:02:22.280 --> 00:02:23.920
on the app you're listening to this one right now

79
00:02:23.920 --> 00:02:25.040
and hit that follow button.

80
00:02:25.040 --> 00:02:28.320
Thank you so, so, so much.

81
00:02:28.760 --> 00:02:35.760
Dr. Alex Tatum.

82
00:02:39.000 --> 00:02:42.080
There's this word that has exploded in society in recent times.

83
00:02:42.080 --> 00:02:44.080
In fact, when I look at the data,

84
00:02:44.080 --> 00:02:46.400
people searching this word has increased

85
00:02:46.400 --> 00:02:49.880
by 400% just recently.

86
00:02:49.880 --> 00:02:52.600
And that word is peptides.

87
00:02:52.600 --> 00:02:55.480
I have no idea what peptides are.

88
00:02:55.480 --> 00:02:57.680
I'm someone that wants to be healthy.

89
00:02:57.720 --> 00:03:00.440
I want to start to my health, wants to live long,

90
00:03:00.440 --> 00:03:02.160
doesn't, doesn't love aging.

91
00:03:02.160 --> 00:03:03.280
Yeah.

92
00:03:03.280 --> 00:03:06.360
And I'm told that this word peptides is somewhat linked to it.

93
00:03:06.360 --> 00:03:08.240
So I've brought you here because you're an expert

94
00:03:08.240 --> 00:03:10.920
in the subject matter of what's your videos on YouTube.

95
00:03:10.920 --> 00:03:13.600
To start at the very beginning, Dr. Alex, sure.

96
00:03:13.600 --> 00:03:15.440
What the hell is a peptide?

97
00:03:15.440 --> 00:03:19.080
Peptides are a structural class of medications.

98
00:03:19.080 --> 00:03:21.120
The best way to think about peptides

99
00:03:21.120 --> 00:03:23.160
is that just like we have small molecules,

100
00:03:23.160 --> 00:03:25.520
which are drugs that are very small,

101
00:03:25.520 --> 00:03:28.600
taken in a pill, and have a wide-ranging effect

102
00:03:28.600 --> 00:03:31.520
throughout the body, peptides are derived

103
00:03:31.520 --> 00:03:34.600
from little pieces of amino acids,

104
00:03:34.600 --> 00:03:37.960
which think of them as the Legos that make up the human body,

105
00:03:37.960 --> 00:03:40.000
the Legos that make up proteins.

106
00:03:40.000 --> 00:03:43.600
These are fragments of proteins that are designed

107
00:03:43.600 --> 00:03:46.320
to specifically target certain receptors

108
00:03:46.320 --> 00:03:49.280
and affect cells in a very targeted fashion.

109
00:03:49.280 --> 00:03:53.600
Or a best way to think about it is a very specific targeted key

110
00:03:53.600 --> 00:03:55.280
to unlock a very specific lock.

111
00:03:55.360 --> 00:03:57.400
So instead of a small molecule

112
00:03:57.400 --> 00:04:00.280
that may have a wide-ranging effect throughout the body,

113
00:04:00.280 --> 00:04:02.760
peptides are much, much more focused.

114
00:04:02.760 --> 00:04:05.760
So you've got different types of Lego cubes here.

115
00:04:05.760 --> 00:04:08.160
Would they be different types of peptides

116
00:04:08.160 --> 00:04:10.720
or are they different types of amino acids

117
00:04:10.720 --> 00:04:12.360
that come together to make a peptide?

118
00:04:12.360 --> 00:04:15.360
The best way to think about it is my son loves Legos,

119
00:04:15.360 --> 00:04:17.680
which is why I'm glad we have these here.

120
00:04:17.680 --> 00:04:19.880
But he can take the same set of Legos

121
00:04:19.880 --> 00:04:22.240
and he can build a rocket ship.

122
00:04:22.240 --> 00:04:23.920
And then just a few minutes later,

123
00:04:23.920 --> 00:04:27.960
he can build a pirate ship and then he builds a race car.

124
00:04:27.960 --> 00:04:29.280
And he's using the same Legos,

125
00:04:29.280 --> 00:04:31.600
but he's creating very, very different things

126
00:04:31.600 --> 00:04:33.960
that all do very, very different things.

127
00:04:33.960 --> 00:04:36.520
And so peptides have become incredibly popular

128
00:04:36.520 --> 00:04:39.560
because yes, we have some really fascinating peptides

129
00:04:39.560 --> 00:04:41.840
that can help with anti-aging, with healing

130
00:04:41.840 --> 00:04:42.680
and with tissue repair.

131
00:04:42.680 --> 00:04:44.680
And we're gonna talk about some of those, hopefully.

132
00:04:44.680 --> 00:04:46.720
But they can do so much more than that.

133
00:04:46.720 --> 00:04:48.840
The first peptide that was actually isolated

134
00:04:48.840 --> 00:04:52.240
and used in medicine was insulin back in 1921.

135
00:04:52.280 --> 00:04:55.960
And then all the way in 1985 in the world of urology,

136
00:04:55.960 --> 00:04:58.440
which is where I was trained, we had luper-lied,

137
00:04:58.440 --> 00:05:01.200
which is a different peptide that again,

138
00:05:01.200 --> 00:05:02.400
also a peptide like insulin,

139
00:05:02.400 --> 00:05:04.760
but instead of having wide-ranging metabolic effects,

140
00:05:04.760 --> 00:05:06.000
it had an endocrine effect.

141
00:05:06.000 --> 00:05:09.600
It was designed to shut down the production of testosterone

142
00:05:09.600 --> 00:05:11.320
for prostate cancer patients

143
00:05:11.320 --> 00:05:13.920
that needed to have their testosterone taken away.

144
00:05:13.920 --> 00:05:14.760
Interesting.

145
00:05:14.760 --> 00:05:16.120
Okay, so insulin's a peptide.

146
00:05:16.120 --> 00:05:20.040
Insulin's a peptide because it's a series of amino acids

147
00:05:20.040 --> 00:05:21.320
that are put together.

148
00:05:21.360 --> 00:05:23.880
Okay, so you said that the combination of amino acids

149
00:05:23.880 --> 00:05:25.000
forms a key.

150
00:05:25.000 --> 00:05:26.280
So what is the lock?

151
00:05:26.280 --> 00:05:29.360
The lock could be a cellular receptor.

152
00:05:29.360 --> 00:05:32.480
It could actually be regulating a certain pathway

153
00:05:32.480 --> 00:05:33.520
within the cell.

154
00:05:33.520 --> 00:05:34.800
Okay, so let me repeat this back to you

155
00:05:34.800 --> 00:05:35.800
to make sure I understand it.

156
00:05:35.800 --> 00:05:39.960
So peptides are like a key, which you can make

157
00:05:39.960 --> 00:05:42.680
by configuring amino acids in a certain way.

158
00:05:42.680 --> 00:05:45.960
And there's different locks in our body

159
00:05:45.960 --> 00:05:47.440
that these keys can go into.

160
00:05:47.440 --> 00:05:49.720
So if I take, we've got some peptides

161
00:05:49.720 --> 00:05:51.280
in the front of us here.

162
00:05:51.280 --> 00:05:54.320
So a good way to think about it is this.

163
00:05:54.320 --> 00:05:57.680
If you've got a hammer, right?

164
00:05:57.680 --> 00:05:59.560
Which is what a lot of small molecules are.

165
00:05:59.560 --> 00:06:01.080
Like you can do a lot with that, right?

166
00:06:01.080 --> 00:06:03.240
Like you could hammer in a nail.

167
00:06:03.240 --> 00:06:04.800
But if you try to use that hammer

168
00:06:04.800 --> 00:06:06.600
when you're trying to put in a screw

169
00:06:06.600 --> 00:06:09.560
or you're trying to put together a table

170
00:06:09.560 --> 00:06:10.760
that you got from IKEA,

171
00:06:10.760 --> 00:06:12.960
it may not always end the way that you want to.

172
00:06:12.960 --> 00:06:14.400
And that's the problem that we have

173
00:06:14.400 --> 00:06:15.960
with a lot of small molecules.

174
00:06:15.960 --> 00:06:17.560
It's not that they don't do what we want them to.

175
00:06:17.560 --> 00:06:19.320
They do a lot of other things

176
00:06:19.320 --> 00:06:20.680
while they're at that job

177
00:06:20.680 --> 00:06:22.880
that can have significant negative side effects.

178
00:06:22.880 --> 00:06:25.680
Which is why a lot of these small molecules

179
00:06:25.680 --> 00:06:27.120
actually don't make it all the way

180
00:06:27.120 --> 00:06:29.360
through the FDA approval process

181
00:06:29.360 --> 00:06:31.520
because we find something, it does what we want to do.

182
00:06:31.520 --> 00:06:34.520
But it has significant safety concerns down the line, right?

183
00:06:34.520 --> 00:06:37.280
Now, what we see with peptides, for example,

184
00:06:37.280 --> 00:06:38.800
I've got in my hand right now,

185
00:06:38.800 --> 00:06:41.760
a little vial labeled BPC157.

186
00:06:41.760 --> 00:06:43.760
This is probably one of the most popular peptides

187
00:06:43.760 --> 00:06:45.440
that we're talking about right now.

188
00:06:45.440 --> 00:06:49.120
Because BPC157 is a synthetic version

189
00:06:49.120 --> 00:06:52.680
of a naturally found peptide in the gut.

190
00:06:52.680 --> 00:06:56.560
But what this actually does is it enhances

191
00:06:56.560 --> 00:06:59.160
blood vessel growth in areas of injury.

192
00:06:59.160 --> 00:07:00.200
And it kind of makes sense

193
00:07:00.200 --> 00:07:01.880
because if you think about it,

194
00:07:01.880 --> 00:07:06.440
our gut, our stomach, is really just this bag of acid

195
00:07:06.440 --> 00:07:08.320
that sits inside of our abdomen.

196
00:07:08.320 --> 00:07:10.440
And yet somehow you and I are here talking to each other

197
00:07:10.440 --> 00:07:11.720
and our bodies aren't eating themselves.

198
00:07:11.720 --> 00:07:12.640
Well, how does that work?

199
00:07:13.040 --> 00:07:15.680
Well, it's because we've developed a lot of really robust

200
00:07:15.680 --> 00:07:18.560
systems to encourage healing of the gastric lining.

201
00:07:18.560 --> 00:07:21.520
And so the idea is, well, if this is one of the compounds

202
00:07:21.520 --> 00:07:22.360
that can help do that,

203
00:07:22.360 --> 00:07:24.800
and it's been proven in multiple animal models.

204
00:07:24.800 --> 00:07:27.040
For example, they have completely transacted

205
00:07:27.040 --> 00:07:29.360
the Achilles tendon in rats.

206
00:07:29.360 --> 00:07:30.320
And they've transacted.

207
00:07:30.320 --> 00:07:31.160
Transsected.

208
00:07:31.160 --> 00:07:33.080
So they've cut across the Achilles tendon.

209
00:07:33.080 --> 00:07:35.480
So not just a small injury that you or I might experience

210
00:07:35.480 --> 00:07:37.600
in the gym where we pull it or strain it,

211
00:07:37.600 --> 00:07:40.920
but actually surgically cut the Achilles tendon.

212
00:07:40.920 --> 00:07:42.720
And then they administer it to rats

213
00:07:42.720 --> 00:07:45.480
and they are healing spontaneously

214
00:07:45.480 --> 00:07:48.240
with administration of BPC157.

215
00:07:48.240 --> 00:07:50.160
If you have an Achilles tendon injury

216
00:07:50.160 --> 00:07:53.080
and you're a rat, BPC157 is one of the best things

217
00:07:53.080 --> 00:07:54.280
that you can ever have.

218
00:07:54.280 --> 00:07:56.080
Now, that is not a one-to-one translation

219
00:07:56.080 --> 00:07:57.760
to what we might see in humans,

220
00:07:57.760 --> 00:08:00.640
but as we talked about earlier with our point on safety,

221
00:08:00.640 --> 00:08:03.200
when they are studying BPC157,

222
00:08:03.200 --> 00:08:07.080
we try to look for something called the LD1 or the LD50.

223
00:08:07.080 --> 00:08:08.760
How much can I give this to someone

224
00:08:08.760 --> 00:08:11.800
until 50% of the population that receives that dose

225
00:08:11.800 --> 00:08:13.840
doesn't do well or dies?

226
00:08:13.840 --> 00:08:16.320
That's called the LD50 dose.

227
00:08:16.320 --> 00:08:19.640
We have yet to figure out what the LD1 dose is for this,

228
00:08:19.640 --> 00:08:21.800
which is the amount that it would take

229
00:08:21.800 --> 00:08:24.040
to hurt even 1% of the population

230
00:08:24.040 --> 00:08:27.360
because it is so incredibly well tolerated.

231
00:08:27.360 --> 00:08:30.480
So just giving you an example of this as a compound

232
00:08:30.480 --> 00:08:32.840
that can have profound healing effects

233
00:08:32.840 --> 00:08:35.960
at least in our animal models that we've seen so far.

234
00:08:36.000 --> 00:08:40.680
But so far, we haven't seen any precipitous negative effects

235
00:08:40.680 --> 00:08:43.560
in human patients when taking this, okay?

236
00:08:43.560 --> 00:08:45.040
But we need more data.

237
00:08:45.040 --> 00:08:47.600
I am mind blown and I'm very, very excited.

238
00:08:47.600 --> 00:08:50.360
We've got all of the several peptides here in front of us.

239
00:08:50.360 --> 00:08:51.200
I want to go through all of that

240
00:08:51.200 --> 00:08:53.280
and understand which ones do which things.

241
00:08:53.280 --> 00:08:57.080
There's a bigger question here, which is, why now?

242
00:08:57.080 --> 00:09:00.480
Why have the subject of peptides suddenly exploded

243
00:09:00.480 --> 00:09:02.800
into society's consciousness?

244
00:09:02.800 --> 00:09:03.640
What's going on?

245
00:09:03.640 --> 00:09:04.480
What's the big picture?

246
00:09:04.480 --> 00:09:06.320
So this is really interesting.

247
00:09:06.320 --> 00:09:10.280
In 2013, there was actually a court case in the United States.

248
00:09:10.280 --> 00:09:13.400
It was the sort of, it was called myriad genetics case.

249
00:09:13.400 --> 00:09:15.720
This was the company that actually patented

250
00:09:15.720 --> 00:09:17.560
the BRCA1 and BRCA2 genes.

251
00:09:17.560 --> 00:09:20.040
They discovered the genes that cause breast cancer, all right?

252
00:09:20.040 --> 00:09:21.400
This was mind blowing.

253
00:09:21.400 --> 00:09:23.000
They identified the specific genes

254
00:09:23.000 --> 00:09:24.440
that would predispose patients

255
00:09:24.440 --> 00:09:26.480
to developing both breast ovarian

256
00:09:26.480 --> 00:09:28.280
and since we've learned also prostate cancer.

257
00:09:28.280 --> 00:09:30.680
It was a fantastic discovery, but they patented it.

258
00:09:30.680 --> 00:09:33.480
And they said, we now own this alien intellectual property.

259
00:09:33.640 --> 00:09:34.960
And then everyone else said,

260
00:09:34.960 --> 00:09:36.560
don't I know, that's the human body.

261
00:09:36.560 --> 00:09:37.600
You can't patent that.

262
00:09:37.600 --> 00:09:40.480
And the Supreme Court actually cited the argument

263
00:09:40.480 --> 00:09:42.080
saying that if something is natural,

264
00:09:42.080 --> 00:09:43.720
it's found within us, okay?

265
00:09:43.720 --> 00:09:46.120
I can't patent your muscle cells, right?

266
00:09:46.120 --> 00:09:47.240
Which is a wonderful thing,

267
00:09:47.240 --> 00:09:50.480
but the unintentional byproduct of that

268
00:09:50.480 --> 00:09:52.040
is all of a sudden,

269
00:09:52.040 --> 00:09:54.520
Barma had no incentive whatsoever

270
00:09:54.520 --> 00:09:57.600
to pursue really promising compounds

271
00:09:57.600 --> 00:09:59.640
that they could not monetize.

272
00:09:59.640 --> 00:10:01.560
So that happens in 2013.

273
00:10:01.560 --> 00:10:04.880
At the same time, I believe it was around 2012, 2013,

274
00:10:04.880 --> 00:10:07.960
there was a terrible event that happened in New England

275
00:10:07.960 --> 00:10:09.960
where there was a compounding pharmacy

276
00:10:09.960 --> 00:10:11.400
that was not doing the right thing

277
00:10:11.400 --> 00:10:14.800
and they ended up having a bunch of contaminated specimens

278
00:10:14.800 --> 00:10:17.920
that caused a fungal meningitis.

279
00:10:17.920 --> 00:10:19.400
A bunch of patients got really sick.

280
00:10:19.400 --> 00:10:21.120
It was a huge scandal.

281
00:10:21.120 --> 00:10:23.240
And all of a sudden, the FDA stepped in and said,

282
00:10:23.240 --> 00:10:25.400
hey, historically, all right,

283
00:10:25.400 --> 00:10:27.320
states have been allowed to regulate

284
00:10:27.320 --> 00:10:28.600
compounding pharmacies themselves,

285
00:10:28.600 --> 00:10:30.080
but we need some federal oversight here

286
00:10:30.120 --> 00:10:31.960
because this is not acceptable.

287
00:10:31.960 --> 00:10:33.040
Completely agree with that.

288
00:10:33.040 --> 00:10:36.680
And they introduced a new set of regulations

289
00:10:36.680 --> 00:10:38.720
on top of compounding pharmacies,

290
00:10:38.720 --> 00:10:41.520
basically saying what you can and cannot make.

291
00:10:41.520 --> 00:10:42.960
And what they eventually said is,

292
00:10:42.960 --> 00:10:44.880
well, you can only make three things.

293
00:10:44.880 --> 00:10:48.760
You can make things that are in the USP United States

294
00:10:48.760 --> 00:10:50.200
of Pharmacopeia, okay?

295
00:10:50.200 --> 00:10:53.240
Things that have been well described, already published.

296
00:10:53.240 --> 00:10:56.280
Things are already in drugs that are already on the market

297
00:10:56.280 --> 00:10:59.120
or three, things that are on a very specific list

298
00:10:59.280 --> 00:11:01.240
that we're going to give you, okay?

299
00:11:01.240 --> 00:11:04.320
And in that list, they actually included

300
00:11:04.320 --> 00:11:06.840
a lot of these very promising compounds

301
00:11:06.840 --> 00:11:09.800
that were stuck in drug development, limbo.

302
00:11:09.800 --> 00:11:11.840
And you say compounding pharmacies.

303
00:11:11.840 --> 00:11:12.680
You said that a few times.

304
00:11:12.680 --> 00:11:13.880
What is a compounding pharmacy,

305
00:11:13.880 --> 00:11:15.320
just so I'm carrying the definition?

306
00:11:15.320 --> 00:11:18.280
Back in the 1800s or early 1900s.

307
00:11:18.280 --> 00:11:19.400
If you ever needed a medication,

308
00:11:19.400 --> 00:11:21.680
you go see the pharmacist who had a shop down the road

309
00:11:21.680 --> 00:11:23.560
and he would actually make your medication in front of you

310
00:11:23.560 --> 00:11:24.520
and he would do that custom

311
00:11:24.520 --> 00:11:26.560
for every single patient that came by, all right?

312
00:11:26.560 --> 00:11:29.080
It was only since the advent of modern factories

313
00:11:29.120 --> 00:11:31.480
that we had the modern pharmaceutical industry come about.

314
00:11:31.480 --> 00:11:33.480
But the truth is, is that, again,

315
00:11:33.480 --> 00:11:34.680
that's kind of paint by numbers.

316
00:11:34.680 --> 00:11:36.280
You're creating this one pill

317
00:11:36.280 --> 00:11:38.520
and it always seemed kind of crazy

318
00:11:38.520 --> 00:11:42.520
that the adult dose is one standardized dose for all adults.

319
00:11:42.520 --> 00:11:45.080
Like if you look at what your body composition is

320
00:11:45.080 --> 00:11:46.120
versus some of my patients,

321
00:11:46.120 --> 00:11:48.000
why is the dose in your blood pressure medicine

322
00:11:48.000 --> 00:11:49.920
the exact same, that doesn't seem to be quite right?

323
00:11:49.920 --> 00:11:51.480
But it is what it is.

324
00:11:51.480 --> 00:11:53.520
So when patients fall outside of that

325
00:11:53.520 --> 00:11:55.120
and they need custom medication,

326
00:11:55.120 --> 00:11:57.080
we still have those people

327
00:11:57.080 --> 00:11:59.560
who make custom formulations of medications.

328
00:11:59.560 --> 00:12:01.720
But instead of it being just your local pharmacist,

329
00:12:01.720 --> 00:12:03.040
use your gun mortar and pestle

330
00:12:03.040 --> 00:12:05.080
and it was creating something in his back office.

331
00:12:05.080 --> 00:12:07.920
These are now large sophisticated industrial operations

332
00:12:07.920 --> 00:12:10.280
that can make custom formulations for patients.

333
00:12:10.280 --> 00:12:11.120
All right.

334
00:12:11.120 --> 00:12:12.680
I think the important context for people

335
00:12:12.680 --> 00:12:15.120
that don't understand how drug development occurs

336
00:12:15.120 --> 00:12:17.840
is that to get chemicals like the ones we have in front

337
00:12:17.840 --> 00:12:20.480
of us on the table through FDA approval,

338
00:12:20.480 --> 00:12:22.840
you've got to spend millions and millions and millions of dollars.

339
00:12:22.840 --> 00:12:24.040
Tens if not hundreds and millions of dollars.

340
00:12:24.040 --> 00:12:25.440
Sometimes hundreds and millions of dollars.

341
00:12:25.480 --> 00:12:27.000
An incredible amount of money.

342
00:12:27.000 --> 00:12:29.160
And if you know you can't protect it,

343
00:12:29.160 --> 00:12:30.440
once you spend a hundred million dollars,

344
00:12:30.440 --> 00:12:32.680
you have no incentive to just do charity work.

345
00:12:32.680 --> 00:12:33.880
Absolutely not, okay?

346
00:12:33.880 --> 00:12:35.720
Because you have shareholders

347
00:12:35.720 --> 00:12:37.480
and you have to make payroll.

348
00:12:37.480 --> 00:12:39.800
And so because drug development is so expensive,

349
00:12:39.800 --> 00:12:43.960
there is no incentive for commercial pharmaceutical companies

350
00:12:43.960 --> 00:12:46.400
to pursue the development of these compounds.

351
00:12:46.400 --> 00:12:48.400
And then on the other side of that,

352
00:12:48.400 --> 00:12:50.040
well, we have compounding pharmacies

353
00:12:50.040 --> 00:12:52.200
that for them it makes sense.

354
00:12:52.200 --> 00:12:53.800
What if we could just make these compounds

355
00:12:53.800 --> 00:12:54.920
and then sell them directly to patients?

356
00:12:54.920 --> 00:12:56.280
We make a small margin when we sell it.

357
00:12:56.280 --> 00:12:57.640
This makes sense for us.

358
00:12:57.640 --> 00:13:00.360
Well, they could do that starting in about 2014

359
00:13:00.360 --> 00:13:02.600
whenever that legislation finished, all right?

360
00:13:02.600 --> 00:13:03.640
What did it do?

361
00:13:03.640 --> 00:13:07.920
Essentially what it did is it gave a assignment

362
00:13:07.920 --> 00:13:09.720
to each one of these compounds.

363
00:13:09.720 --> 00:13:11.440
It was either gonna be category one,

364
00:13:11.440 --> 00:13:13.920
which is you can compound this.

365
00:13:13.920 --> 00:13:15.000
This is on our specific list

366
00:13:15.000 --> 00:13:17.800
of approved, compoundable drug ingredients.

367
00:13:17.800 --> 00:13:21.120
Number two was, hey, we see some negative safety signals here.

368
00:13:21.120 --> 00:13:22.400
You cannot make this, okay?

369
00:13:22.400 --> 00:13:24.400
Something goes on category two, it's forbidden.

370
00:13:24.560 --> 00:13:25.560
And then we have category three,

371
00:13:25.560 --> 00:13:27.480
which is we just need more information.

372
00:13:27.480 --> 00:13:29.440
And all of these original compounds,

373
00:13:29.440 --> 00:13:31.080
these peptides that were so interested in now,

374
00:13:31.080 --> 00:13:34.840
were originally on that first list, category one, all right?

375
00:13:34.840 --> 00:13:37.520
And so they were able to be compounded.

376
00:13:37.520 --> 00:13:38.600
We could prescribe them in patients.

377
00:13:38.600 --> 00:13:40.440
I prescribed them to patients, all right?

378
00:13:40.440 --> 00:13:42.920
From 2014 onward.

379
00:13:42.920 --> 00:13:46.800
But then in 2023, and the FDA at that time,

380
00:13:46.800 --> 00:13:49.640
switched all of those peptides, 19 of them

381
00:13:49.640 --> 00:13:52.920
that were popular to category two, and then they were banned.

382
00:13:52.920 --> 00:13:55.520
Over night, we got notifications in our email inboxes

383
00:13:55.520 --> 00:13:56.920
from our compounding pharmacy partner saying,

384
00:13:56.920 --> 00:13:59.720
hey, we can't make this anymore, we're sorry.

385
00:13:59.720 --> 00:14:00.760
So I've got two questions there.

386
00:14:00.760 --> 00:14:01.600
Yes.

387
00:14:01.600 --> 00:14:04.240
The first is, when you were prescribing

388
00:14:04.240 --> 00:14:05.880
these peptides to your patient.

389
00:14:05.880 --> 00:14:07.160
Yes.

390
00:14:07.160 --> 00:14:09.400
What are you saying, incredible results?

391
00:14:09.400 --> 00:14:10.440
Very much so.

392
00:14:10.440 --> 00:14:13.240
Very much, again, you have to use the right key

393
00:14:13.240 --> 00:14:15.000
for the right lock, okay?

394
00:14:15.000 --> 00:14:18.160
But I think a really good example, all right?

395
00:14:18.160 --> 00:14:22.360
So there is a compound that is not technically a peptide.

396
00:14:22.360 --> 00:14:24.880
It is a small molecule, but it was lumped in with all of these

397
00:14:24.880 --> 00:14:27.880
and was the victim to the same process.

398
00:14:27.880 --> 00:14:31.120
Something called MK677, also known as Ibutamorin.

399
00:14:31.120 --> 00:14:34.280
So this is a small molecule, but when a patient takes it,

400
00:14:34.280 --> 00:14:35.480
it's orally available.

401
00:14:35.480 --> 00:14:37.520
It binds to this receptor called Grellen,

402
00:14:37.520 --> 00:14:39.240
and it actually stimulates the release

403
00:14:39.240 --> 00:14:40.720
of significant growth hormone.

404
00:14:40.720 --> 00:14:43.240
But what was really interesting is that it would actually

405
00:14:43.240 --> 00:14:45.320
stimulate hunger a profound amount.

406
00:14:45.320 --> 00:14:48.160
And all of a sudden, patients that were struggling

407
00:14:48.160 --> 00:14:49.440
with cacaxia, okay?

408
00:14:49.440 --> 00:14:51.680
So being very, very thin, very malnourished,

409
00:14:51.680 --> 00:14:53.240
maybe they're going through cancer treatment.

410
00:14:53.240 --> 00:14:54.920
Grellen's the thing that makes us feel hungry, right?

411
00:14:54.920 --> 00:14:56.280
Absolutely, yeah.

412
00:14:56.280 --> 00:14:58.920
So they were able to stimulate the hunger response

413
00:14:58.920 --> 00:15:02.760
and patients were actually able to eat more to meet caloric goals.

414
00:15:02.760 --> 00:15:07.320
And so this was a medication that was fantastically effective at that.

415
00:15:07.320 --> 00:15:09.760
Again, it had gone through some clinical trials

416
00:15:09.760 --> 00:15:12.760
but was never taken all the way to commercial.

417
00:15:12.760 --> 00:15:14.560
And so it was never gonna be available

418
00:15:14.560 --> 00:15:17.320
from CVS or Walgreens, but you could get it

419
00:15:17.320 --> 00:15:18.960
from a compounding pharmacy.

420
00:15:18.960 --> 00:15:21.440
And so that was one that made a big difference for us.

421
00:15:21.480 --> 00:15:22.920
We also had other peptides.

422
00:15:22.920 --> 00:15:26.160
So GHRP2 and GHRP6 were some of the ones

423
00:15:26.160 --> 00:15:27.800
we were using at that time.

424
00:15:27.800 --> 00:15:31.000
Those are growth hormone releasing peptides

425
00:15:31.000 --> 00:15:33.360
that stimulate the release of your body's natural growth

426
00:15:33.360 --> 00:15:35.440
hormone, which can help with tissue repair,

427
00:15:35.440 --> 00:15:38.600
can also help with fat loss and with building muscle.

428
00:15:38.600 --> 00:15:43.120
We also had BPC157 and we had derivatives

429
00:15:43.120 --> 00:15:44.240
like thymus and beta-4.

430
00:15:44.240 --> 00:15:47.480
These are also compounds that can help stimulate

431
00:15:47.480 --> 00:15:50.840
angiogenesis so making new blood vessels and tissue repair.

432
00:15:50.840 --> 00:15:53.240
So if we have a patient that's injured themselves,

433
00:15:53.240 --> 00:15:56.160
maybe we could help them get back at life faster.

434
00:15:56.160 --> 00:15:57.920
These were all things that were used very commonplace

435
00:15:57.920 --> 00:16:01.280
for many years and truthfully they weren't super popular

436
00:16:01.280 --> 00:16:03.200
at the time, we were just using them

437
00:16:03.200 --> 00:16:04.960
and then they were banned overnight.

438
00:16:04.960 --> 00:16:05.960
And they were working.

439
00:16:05.960 --> 00:16:09.360
And they were working and we were not seeing adverse events

440
00:16:09.360 --> 00:16:10.920
which is the most important thing.

441
00:16:10.920 --> 00:16:11.960
What's an adverse event?

442
00:16:11.960 --> 00:16:15.120
An adverse event is a patient has a terrible side effect.

443
00:16:15.120 --> 00:16:17.880
They call you, they have an allergic reaction to something,

444
00:16:17.880 --> 00:16:19.440
they call, they've got shortness of breath

445
00:16:19.480 --> 00:16:21.200
and it's a direct result of the medication

446
00:16:21.200 --> 00:16:22.040
that you gave them.

447
00:16:22.040 --> 00:16:23.320
It was working, it was working

448
00:16:23.320 --> 00:16:25.640
and by all accounts seem to be incredibly safe.

449
00:16:25.640 --> 00:16:26.560
And then they banned it.

450
00:16:26.560 --> 00:16:27.680
And then they banned it.

451
00:16:27.680 --> 00:16:28.520
Why?

452
00:16:28.520 --> 00:16:29.560
That's a great question.

453
00:16:29.560 --> 00:16:33.320
So officially what happened is there is a meeting

454
00:16:33.320 --> 00:16:35.320
where they brought together the experts at the time

455
00:16:35.320 --> 00:16:38.200
and they said there is insufficient data for us to say

456
00:16:38.200 --> 00:16:39.400
that these are safe because again,

457
00:16:39.400 --> 00:16:41.920
they had not gone through the full FDA approval process.

458
00:16:41.920 --> 00:16:45.120
And so as a result of lacking that data,

459
00:16:45.120 --> 00:16:46.960
we're gonna say that they're too dangerous.

460
00:16:46.960 --> 00:16:48.680
Now there wasn't any evidence of any of that

461
00:16:48.680 --> 00:16:49.520
in the population.

462
00:16:49.520 --> 00:16:51.280
These were widely used at the time.

463
00:16:51.280 --> 00:16:54.840
Potentially we had commercial pharmaceutical companies

464
00:16:54.840 --> 00:16:57.640
saying, well, hey, this is people spending money

465
00:16:57.640 --> 00:17:01.120
on a compound, on something that isn't coming to us.

466
00:17:01.120 --> 00:17:03.480
So, hey, like we love medicine,

467
00:17:03.480 --> 00:17:06.000
but maybe only when it's our medicine.

468
00:17:06.000 --> 00:17:08.760
And so there's concern that that was at play as well.

469
00:17:08.760 --> 00:17:10.640
And so there is not a great paper trail

470
00:17:10.640 --> 00:17:12.080
and there's not a great explanation why.

471
00:17:12.080 --> 00:17:13.640
And that's something that's been iterated

472
00:17:13.640 --> 00:17:16.720
by our current administration from RFK himself.

473
00:17:17.000 --> 00:17:20.080
He himself has characterized that move down in 2023

474
00:17:20.080 --> 00:17:21.000
as being illegal.

475
00:17:21.000 --> 00:17:23.120
With everything you know about the medical industry,

476
00:17:23.120 --> 00:17:26.720
do you think it is plausible that big pharma?

477
00:17:26.720 --> 00:17:28.360
110%.

478
00:17:28.360 --> 00:17:31.240
Didn't one 110%.

479
00:17:31.240 --> 00:17:32.720
These in the hands of regular people

480
00:17:32.720 --> 00:17:35.560
because they can't patent this and it's powerful.

481
00:17:35.560 --> 00:17:38.880
So ultimately, the way to think about it is this.

482
00:17:41.920 --> 00:17:44.280
Pharma may not have a compound

483
00:17:44.280 --> 00:17:47.360
that directly competes for BBC 157.

484
00:17:47.360 --> 00:17:48.480
BBC 157.

485
00:17:48.480 --> 00:17:51.360
So this is the medication or the peptide

486
00:17:51.360 --> 00:17:54.600
that can aid with healing after an injury, okay?

487
00:17:54.600 --> 00:17:57.240
So it's not necessarily there's direct competition.

488
00:17:57.240 --> 00:18:00.360
But at the end of the day, your average patient

489
00:18:00.360 --> 00:18:02.160
going throughout their daily life

490
00:18:02.160 --> 00:18:05.160
only has so much money that they can spend on medicine.

491
00:18:05.160 --> 00:18:09.800
And $10, $15, however much money that goes to this

492
00:18:09.800 --> 00:18:11.520
doesn't go to a prescription drug

493
00:18:11.520 --> 00:18:13.680
from a commercial pharmaceutical company.

494
00:18:13.680 --> 00:18:15.360
And so there is real concern

495
00:18:15.360 --> 00:18:17.680
that potentially that was at play during that decision.

496
00:18:17.680 --> 00:18:19.360
And you said 110%.

497
00:18:19.360 --> 00:18:21.520
Yeah, well, you know, it's interesting

498
00:18:21.520 --> 00:18:24.920
because you know, I tried to walk a very fine line

499
00:18:24.920 --> 00:18:28.360
between what I can prove versus what I suspect

500
00:18:28.360 --> 00:18:31.400
after being in this space for a long time.

501
00:18:31.400 --> 00:18:33.880
And you know, ultimately, you know,

502
00:18:33.880 --> 00:18:36.720
I don't think it's accurate to characterize

503
00:18:36.720 --> 00:18:39.360
pharmaceutical companies or really any other entity

504
00:18:39.360 --> 00:18:42.360
as being, you know, evil or bad.

505
00:18:42.360 --> 00:18:44.400
And the truth is maybe a little bit more ominous.

506
00:18:44.400 --> 00:18:48.080
The truth is is that they are these large machines

507
00:18:48.080 --> 00:18:50.320
that are designed to prioritize profit over everything.

508
00:18:50.320 --> 00:18:51.160
Yeah.

509
00:18:51.160 --> 00:18:52.400
And that's everything.

510
00:18:52.400 --> 00:18:54.240
I think this is one of the really interesting observations

511
00:18:54.240 --> 00:18:56.200
I've had the higher I've gone in my career

512
00:18:56.200 --> 00:18:59.080
is that oftentimes we had about the Illuminati.

513
00:18:59.080 --> 00:18:59.920
Like when I was growing up I was like,

514
00:18:59.920 --> 00:19:00.960
oh, there's this Illuminati.

515
00:19:00.960 --> 00:19:01.800
Yeah.

516
00:19:01.800 --> 00:19:03.640
And you think of it as these like shadow-headed people

517
00:19:03.640 --> 00:19:05.720
that get together and decide evil things.

518
00:19:05.720 --> 00:19:07.160
But the further I've gone in business,

519
00:19:07.160 --> 00:19:08.680
the more I've realized that the Illuminati

520
00:19:08.680 --> 00:19:10.680
or these evil forces are actually just machines

521
00:19:10.800 --> 00:19:12.480
that were designed to optimize for profit.

522
00:19:12.480 --> 00:19:13.320
Correct.

523
00:19:13.320 --> 00:19:14.160
Correct.

524
00:19:14.160 --> 00:19:15.960
So like corporations of Illuminati.

525
00:19:15.960 --> 00:19:16.960
Yeah.

526
00:19:16.960 --> 00:19:19.000
And so I don't actually think that there is necessarily,

527
00:19:19.000 --> 00:19:21.880
you know, a group of maniacal individuals,

528
00:19:21.880 --> 00:19:23.400
you know, the legion of doom, you know,

529
00:19:23.400 --> 00:19:25.600
plotting to like take away your health.

530
00:19:25.600 --> 00:19:28.240
But at the same time, I think that there are these

531
00:19:28.240 --> 00:19:30.120
large organizations that really couldn't care less

532
00:19:30.120 --> 00:19:31.120
about your health, you know.

533
00:19:31.120 --> 00:19:33.440
They are prioritizing what's important for them.

534
00:19:33.440 --> 00:19:36.200
And regular people just get caught up in the mix.

535
00:19:36.200 --> 00:19:38.240
And what's challenging is that as a physician,

536
00:19:38.240 --> 00:19:40.200
you know, I took a Hippocratic oath.

537
00:19:40.200 --> 00:19:41.880
You know, I care about my patients.

538
00:19:41.880 --> 00:19:43.440
And so those are the people that are in front of me

539
00:19:43.440 --> 00:19:46.320
every single day that are seeking to improve their lives

540
00:19:46.320 --> 00:19:47.240
to recover from injury.

541
00:19:47.240 --> 00:19:48.960
I have, you know, fertility patients

542
00:19:48.960 --> 00:19:50.960
that are just dying to start their family.

543
00:19:50.960 --> 00:19:53.320
And I have patients that are suffering

544
00:19:53.320 --> 00:19:55.600
from hormonal imbalances that haven't felt right in years.

545
00:19:55.600 --> 00:19:57.440
I treat erectile dysfunction in men

546
00:19:57.440 --> 00:19:58.840
that have been struggling for years

547
00:19:58.840 --> 00:20:00.120
after prostate cancer treatment.

548
00:20:00.120 --> 00:20:01.920
I mean, these are people that are broken and hurting.

549
00:20:01.920 --> 00:20:03.720
You want to be able to help them.

550
00:20:03.720 --> 00:20:07.080
And so I feel that is a very strong personal calling

551
00:20:07.080 --> 00:20:09.240
that I have to be that advocate for that patient.

552
00:20:09.240 --> 00:20:11.640
Both in the room, whenever I'm treating them

553
00:20:11.640 --> 00:20:12.600
and taking care of them,

554
00:20:12.600 --> 00:20:14.240
but also when I'm talking to others

555
00:20:14.240 --> 00:20:16.320
and I'm speaking out about these issues.

556
00:20:16.320 --> 00:20:18.400
Like I want access to these medications

557
00:20:18.400 --> 00:20:21.200
because I care about the patients who benefit from them.

558
00:20:22.200 --> 00:20:24.960
So they banned these peptides that we have here.

559
00:20:24.960 --> 00:20:25.800
Correct.

560
00:20:25.800 --> 00:20:26.880
And with that here, two years after the ban,

561
00:20:26.880 --> 00:20:28.520
I believe to roughly two years after that ban.

562
00:20:28.520 --> 00:20:29.360
Yeah.

563
00:20:29.360 --> 00:20:31.360
And suddenly everybody's talking about peptides again.

564
00:20:31.360 --> 00:20:32.200
Yes.

565
00:20:32.200 --> 00:20:33.040
Why? What's going on?

566
00:20:33.040 --> 00:20:37.160
So I think what we're seeing is the forbidden fruit effect

567
00:20:37.160 --> 00:20:39.000
because this was banned and all of a sudden,

568
00:20:39.000 --> 00:20:39.880
oh, well, why they banned it?

569
00:20:39.880 --> 00:20:41.960
Well, it wouldn't have banned it if it weren't working, right?

570
00:20:41.960 --> 00:20:44.480
And we're also seeing the effect of TikTok

571
00:20:44.480 --> 00:20:46.960
and short form content being spread very rapidly,

572
00:20:46.960 --> 00:20:47.920
very virally.

573
00:20:47.920 --> 00:20:50.040
And that's been going on for two years now

574
00:20:50.040 --> 00:20:54.480
combined with a new emphasis from administration leadership

575
00:20:54.480 --> 00:20:56.360
and the HHS and an RFK.

576
00:20:56.360 --> 00:20:59.640
What is the most incredible impact

577
00:20:59.640 --> 00:21:02.280
that you've seen peptides create in a patient?

578
00:21:02.280 --> 00:21:04.680
Oh my gosh, I have a best story for you.

579
00:21:04.720 --> 00:21:09.000
So one of the most frustrating things about my practice

580
00:21:09.000 --> 00:21:12.360
is treating infertility in young men

581
00:21:12.360 --> 00:21:14.760
that have significant metabolic dysfunction.

582
00:21:14.760 --> 00:21:18.080
These are young men that have a low sperm count, right?

583
00:21:18.080 --> 00:21:19.200
So they can't get pregnant

584
00:21:19.200 --> 00:21:21.720
because they just don't have the numbers to make it happen.

585
00:21:21.720 --> 00:21:24.680
And you're looking at them and they're morbidly obese, okay?

586
00:21:24.680 --> 00:21:27.160
They have high insulin resistance, all right?

587
00:21:27.160 --> 00:21:30.440
And their endocrine system has been damaged by that obesity.

588
00:21:30.440 --> 00:21:32.760
So they don't have low testosterone levels

589
00:21:32.760 --> 00:21:34.320
and their brain is not making enough

590
00:21:34.320 --> 00:21:36.360
of the signals to stimulate their testicles.

591
00:21:36.360 --> 00:21:39.360
Now, we have medications that we can use

592
00:21:39.360 --> 00:21:40.600
to help stimulate that,

593
00:21:40.600 --> 00:21:43.360
to make more of that signal stimulate the testicles, right?

594
00:21:43.360 --> 00:21:45.840
But really, what is eating at them,

595
00:21:45.840 --> 00:21:48.520
what is causing this is not that chemical imbalance,

596
00:21:48.520 --> 00:21:51.240
that's the symptom, it's not the problem, okay?

597
00:21:51.240 --> 00:21:53.480
And treating symptoms doesn't really get you very far.

598
00:21:53.480 --> 00:21:55.600
And so I would have patients that I would take care of

599
00:21:55.600 --> 00:21:57.360
and we would never see a significant improvement

600
00:21:57.360 --> 00:21:58.720
in their numbers because losing weight

601
00:21:58.720 --> 00:21:59.920
is really, really hard.

602
00:21:59.920 --> 00:22:02.280
Regardless of all the education and resources

603
00:22:02.360 --> 00:22:03.400
that try to give them.

604
00:22:03.400 --> 00:22:07.320
But now we have peptides in the form of GLP-1 drugs

605
00:22:07.320 --> 00:22:09.600
like semi-glue diet and tersepotide.

606
00:22:09.600 --> 00:22:11.640
And I just saw a patient last week

607
00:22:11.640 --> 00:22:15.120
who increased his sperm count 10 times over

608
00:22:15.120 --> 00:22:19.760
and is now in a normal range because he's lost 100 pounds

609
00:22:19.760 --> 00:22:21.920
due to using tersepotide,

610
00:22:21.920 --> 00:22:24.080
exercising and improving his diet.

611
00:22:24.080 --> 00:22:26.080
And he has totally changed his life.

612
00:22:26.080 --> 00:22:27.360
And that started with a peptide.

613
00:22:27.360 --> 00:22:28.840
It started with a peptide.

614
00:22:28.840 --> 00:22:31.200
So we've got lots of peptides on the table in front of us.

615
00:22:31.200 --> 00:22:32.800
We will go into them individually,

616
00:22:32.800 --> 00:22:35.400
but just can you give me a high level view

617
00:22:35.400 --> 00:22:38.000
of the types of areas in our health and life

618
00:22:38.000 --> 00:22:39.880
that these peptides can help with?

619
00:22:39.880 --> 00:22:41.800
So we've talked there about infertility,

620
00:22:41.800 --> 00:22:44.160
as a downstream consequence of the weight loss

621
00:22:44.160 --> 00:22:46.400
and fixing the metabolic health.

622
00:22:46.400 --> 00:22:48.920
What are the parts of the body to peptides touch?

623
00:22:48.920 --> 00:22:51.040
The best way to think about it is like this.

624
00:22:51.040 --> 00:22:55.280
So peptides are almost like an app on your phone.

625
00:22:55.280 --> 00:22:57.640
So imagine before we had apps,

626
00:22:57.640 --> 00:22:59.800
I'm old enough to remember trying to log on

627
00:22:59.800 --> 00:23:01.840
and do my banking online before we had apps

628
00:23:01.840 --> 00:23:03.600
and gosh, it was so painful, right?

629
00:23:03.600 --> 00:23:04.800
Like there were ways to accomplish things

630
00:23:04.800 --> 00:23:07.280
but they were very inconvenient in a roundabout way.

631
00:23:07.280 --> 00:23:09.840
And now all of a sudden we have these apps on our phone

632
00:23:09.840 --> 00:23:12.640
that can do just about anything except for your laundry, right?

633
00:23:12.640 --> 00:23:14.000
You know, there's some limits to it,

634
00:23:14.000 --> 00:23:15.760
but I mean, really the sky's the limit

635
00:23:15.760 --> 00:23:17.520
from an electronic standpoint.

636
00:23:17.520 --> 00:23:19.400
And really that's what peptides are.

637
00:23:19.400 --> 00:23:21.880
So the thing is is that we have peptides

638
00:23:21.880 --> 00:23:24.400
that can help you lose weight like the GLP1 drugs.

639
00:23:24.400 --> 00:23:28.120
We have peptides that can improve skin quality

640
00:23:28.120 --> 00:23:30.320
like GHKCU.

641
00:23:30.320 --> 00:23:34.240
We have peptides that can help heal your gut like BPC157,

642
00:23:34.240 --> 00:23:36.960
particularly effective and ulcerative colitis,

643
00:23:36.960 --> 00:23:38.520
which is something that's being investigated

644
00:23:38.520 --> 00:23:40.800
with FDA's planned upcoming meeting on it.

645
00:23:40.800 --> 00:23:43.920
We also have peptides that can help with sleep

646
00:23:43.920 --> 00:23:46.400
and with recovering the gland in your brain

647
00:23:46.400 --> 00:23:47.760
that's responsible for melatonin

648
00:23:47.760 --> 00:23:49.800
and regulating your sleep weight cycles.

649
00:23:49.800 --> 00:23:52.480
So the question isn't, you know, what can peptides do?

650
00:23:52.480 --> 00:23:54.480
It's kind of, well, what can't they do?

651
00:23:54.480 --> 00:23:55.960
And if they can't do that yet,

652
00:23:55.960 --> 00:23:58.880
can we develop a peptide that can accomplish that task?

653
00:23:58.880 --> 00:24:00.720
And the answer is probably

654
00:24:00.720 --> 00:24:03.120
and simultaneously while there may be resistance

655
00:24:03.120 --> 00:24:06.000
from pharmaceutical industry in these peptides,

656
00:24:06.000 --> 00:24:08.360
the ones that we're most interested right now,

657
00:24:08.360 --> 00:24:10.680
they have signed multi-billion dollar deals

658
00:24:10.680 --> 00:24:13.440
with other pharmaceutical companies

659
00:24:13.440 --> 00:24:14.800
that are involved in peptide,

660
00:24:14.800 --> 00:24:18.000
a development aided by AI to try and fast track

661
00:24:18.000 --> 00:24:20.000
their own peptide products.

662
00:24:20.000 --> 00:24:20.840
Interesting.

663
00:24:20.840 --> 00:24:23.840
And so we are going to see exponentially more of these products

664
00:24:23.840 --> 00:24:26.600
come down the pipeline from pharmaceutical companies

665
00:24:26.600 --> 00:24:28.240
in the form of commercial products.

666
00:24:28.240 --> 00:24:31.080
And it's worth saying that there was some significant news today.

667
00:24:31.080 --> 00:24:31.920
Correct.

668
00:24:31.920 --> 00:24:33.520
What happened today, but also what's going on?

669
00:24:33.520 --> 00:24:34.560
And just for anyone that doesn't know,

670
00:24:34.560 --> 00:24:36.120
it's April the 15th.

671
00:24:36.120 --> 00:24:37.120
Yes.

672
00:24:37.120 --> 00:24:41.800
So today, we got a press release from the FDA

673
00:24:41.800 --> 00:24:44.560
saying that in July, they are going to consider

674
00:24:44.560 --> 00:24:48.560
seven peptides for removing from category two

675
00:24:48.560 --> 00:24:49.720
back to category one.

676
00:24:49.720 --> 00:24:50.640
We legalizing them.

677
00:24:50.640 --> 00:24:52.160
Legalizing them, okay?

678
00:24:52.160 --> 00:24:56.200
And some of the heavy hitters from that list

679
00:24:56.200 --> 00:25:00.120
include BPC 157, which is the one we talked about

680
00:25:00.120 --> 00:25:01.640
to do with like repair and injury.

681
00:25:01.640 --> 00:25:02.640
Absolutely, okay?

682
00:25:02.640 --> 00:25:05.680
And then we have the brother to that,

683
00:25:05.680 --> 00:25:08.600
which is TV 500, this file over here.

684
00:25:08.600 --> 00:25:11.080
This improves blood flow to an injured area.

685
00:25:11.080 --> 00:25:13.560
You could think of this as sending the soldiers,

686
00:25:13.560 --> 00:25:15.560
as sending the cells that are required

687
00:25:15.560 --> 00:25:17.840
for rebuilding that tissue matrix

688
00:25:17.840 --> 00:25:20.760
that was damaged by a tear or a cut, all right?

689
00:25:20.760 --> 00:25:24.040
On top of that, we're also getting something called

690
00:25:24.040 --> 00:25:26.000
KPV may not have it here,

691
00:25:26.000 --> 00:25:29.360
but that is another peptide that has been linked

692
00:25:29.360 --> 00:25:32.320
to angiogenesis and tissue repair.

693
00:25:32.320 --> 00:25:33.920
We're also getting MOTC.

694
00:25:33.920 --> 00:25:36.640
And you know, some patients will call it exercise in a vial.

695
00:25:36.640 --> 00:25:39.840
It improves your VO2 max and your exercise tolerance

696
00:25:39.840 --> 00:25:42.960
and by up regulating the energy pathway,

697
00:25:42.960 --> 00:25:45.960
basically making more ATP, the energy that we all use to move,

698
00:25:45.960 --> 00:25:48.120
it makes more of that available, all right?

699
00:25:48.120 --> 00:25:52.360
We're also going to get DSIP, epithelon, and CMax,

700
00:25:52.360 --> 00:25:55.200
which are all peptides that affect cognitive function.

701
00:25:55.200 --> 00:25:59.400
So improving thinking, like CMax is a great option for that.

702
00:25:59.400 --> 00:26:02.120
And then DSIP and epithelon both have rules

703
00:26:02.120 --> 00:26:05.520
in regulating sleep and recovery.

704
00:26:05.520 --> 00:26:07.320
Wow. Yeah, pretty wild.

705
00:26:08.480 --> 00:26:10.120
And I've got to say, how does,

706
00:26:10.120 --> 00:26:12.040
so some of them are becoming legalized,

707
00:26:12.040 --> 00:26:13.440
but even the ones that aren't legal right now,

708
00:26:13.440 --> 00:26:14.720
a lot of people are taking them anyway.

709
00:26:14.720 --> 00:26:15.720
Correct.

710
00:26:15.720 --> 00:26:17.960
So my question is how are people getting them?

711
00:26:17.960 --> 00:26:20.240
Listen, I don't want to promote illegal drugs here.

712
00:26:20.240 --> 00:26:21.360
This is not the back of my shirt.

713
00:26:21.360 --> 00:26:22.960
But I just want to know what's going on.

714
00:26:22.960 --> 00:26:25.080
No, this is what this is important to talk about, right?

715
00:26:25.080 --> 00:26:27.720
Can we have to understand like what's going on in the marketplace?

716
00:26:27.720 --> 00:26:30.240
The moment that these drugs were banned

717
00:26:30.240 --> 00:26:32.400
or these medications were banned in 2023,

718
00:26:32.400 --> 00:26:34.280
it was kind of like the United States experimented

719
00:26:34.280 --> 00:26:36.520
banning alcohol, it didn't go very well, right?

720
00:26:36.520 --> 00:26:38.800
All of a sudden, you know, they, you know,

721
00:26:38.800 --> 00:26:41.000
the mob came around and we started, you know,

722
00:26:41.000 --> 00:26:46.120
seeing unregulated saloons and unregulated alcohol production.

723
00:26:46.120 --> 00:26:48.000
And it was contaminated with all this stuff that you didn't want.

724
00:26:48.000 --> 00:26:49.240
And so we're like, people are troubling.

725
00:26:49.240 --> 00:26:50.080
Yeah, exactly.

726
00:26:50.080 --> 00:26:52.320
It's just, it's not a good idea, right?

727
00:26:52.320 --> 00:26:54.280
And so what happened is we banned these

728
00:26:54.280 --> 00:26:55.920
and the gray market stepped in.

729
00:26:55.920 --> 00:26:59.240
And so these are companies that will sell peptides

730
00:26:59.240 --> 00:27:02.240
that have on the label for research use only, all right?

731
00:27:02.240 --> 00:27:04.480
And the idea is that that takes them

732
00:27:04.480 --> 00:27:05.840
out of the FDA's jurisdiction

733
00:27:05.840 --> 00:27:07.120
because they're not selling it for people

734
00:27:07.120 --> 00:27:09.560
to inject into themselves out of the FDA's hands.

735
00:27:09.560 --> 00:27:12.840
I'm just creating a vial of this magical juice

736
00:27:12.840 --> 00:27:15.120
that you can use for your rat, okay?

737
00:27:15.160 --> 00:27:16.000
That's the idea.

738
00:27:16.000 --> 00:27:18.240
We all know that's not what's really happening.

739
00:27:18.240 --> 00:27:20.960
But because there isn't any quality control,

740
00:27:20.960 --> 00:27:23.000
it's kind of like getting gas station sushi.

741
00:27:23.000 --> 00:27:24.200
Like, yeah, you can do it,

742
00:27:24.200 --> 00:27:25.880
but you don't really know if it's sushi

743
00:27:25.880 --> 00:27:27.720
and it may not in very well for you.

744
00:27:27.720 --> 00:27:29.760
And so again, not saying that there aren't

745
00:27:29.760 --> 00:27:32.040
some people who have gotten good results

746
00:27:32.040 --> 00:27:34.680
with research use only peptides,

747
00:27:34.680 --> 00:27:36.120
but again, it's not standardized,

748
00:27:36.120 --> 00:27:38.640
which is why I think moving this back

749
00:27:38.640 --> 00:27:40.560
into the 503A compounding world

750
00:27:40.560 --> 00:27:41.680
is the best thing for everyone.

751
00:27:41.680 --> 00:27:43.360
Which is the legal framework.

752
00:27:43.600 --> 00:27:45.640
Okay, so how does one take a peptide?

753
00:27:45.640 --> 00:27:46.640
That's a great question.

754
00:27:46.640 --> 00:27:48.880
So what's interesting is that as we mentioned,

755
00:27:48.880 --> 00:27:50.280
you know, peptides are just made up

756
00:27:50.280 --> 00:27:52.040
of building blocks of amino acids.

757
00:27:52.040 --> 00:27:55.400
And you know, if you were to go make yourself a protein shake,

758
00:27:55.400 --> 00:27:56.400
you know, what is that gonna look like

759
00:27:56.400 --> 00:27:57.440
from a Lego standpoint?

760
00:27:57.440 --> 00:27:59.880
It just looks like this, a handful of Legos in your hand,

761
00:27:59.880 --> 00:28:00.720
right?

762
00:28:00.720 --> 00:28:01.720
Sort of ground up

763
00:28:01.720 --> 00:28:03.200
and individual pieces, right?

764
00:28:03.200 --> 00:28:04.040
Okay.

765
00:28:04.040 --> 00:28:07.040
The thing is is that your gut is designed to break up

766
00:28:07.040 --> 00:28:09.520
any sort of protein that you ingest

767
00:28:09.520 --> 00:28:11.640
orally into these little pieces.

768
00:28:11.720 --> 00:28:13.360
And so if you were to say,

769
00:28:13.360 --> 00:28:17.240
I don't know, drink some of, you know, this TB 500,

770
00:28:17.240 --> 00:28:18.480
your body wouldn't be able to tell the difference

771
00:28:18.480 --> 00:28:19.720
between that and a piece of chicken

772
00:28:19.720 --> 00:28:21.120
because it would break it all apart.

773
00:28:21.120 --> 00:28:22.000
It would break it all apart.

774
00:28:22.000 --> 00:28:24.840
Now, there are some very unique exceptions to that.

775
00:28:24.840 --> 00:28:27.560
There's a form of BPC157 that actually is tolerated

776
00:28:27.560 --> 00:28:29.480
in the gut, but by and large,

777
00:28:29.480 --> 00:28:32.080
overwhelming majority of these have to be injected,

778
00:28:32.080 --> 00:28:34.440
either subcutaneously or into the muscle.

779
00:28:34.440 --> 00:28:35.760
And that's usually a preference.

780
00:28:35.760 --> 00:28:37.640
Subcutaneous being 100.

781
00:28:37.640 --> 00:28:38.560
Just underneath the skin.

782
00:28:38.560 --> 00:28:39.560
You know, as I tell patients,

783
00:28:39.560 --> 00:28:41.200
just pinch an inch and inject under the skin,

784
00:28:41.200 --> 00:28:42.920
we do that for a lot of other medications as well.

785
00:28:42.920 --> 00:28:44.200
Is that what this is?

786
00:28:44.200 --> 00:28:45.040
Yeah.

787
00:28:45.040 --> 00:28:47.320
So this is a prescription mongaro pen.

788
00:28:47.320 --> 00:28:51.160
So mongaro is the brand name for trizepa type, all right?

789
00:28:51.160 --> 00:28:54.920
Trizepa type being the leading GLP1 product right now

790
00:28:54.920 --> 00:28:55.760
from Lily.

791
00:28:55.760 --> 00:28:59.400
So this produces more weight loss per milligram

792
00:28:59.400 --> 00:29:01.640
than any other product that we've got out right now.

793
00:29:01.640 --> 00:29:04.840
Is this the mechanism in which people inject peptides?

794
00:29:04.840 --> 00:29:05.880
A little bit different.

795
00:29:05.880 --> 00:29:08.280
So this is an auto-injector pen.

796
00:29:08.280 --> 00:29:10.000
And so what you do is you're able to actually

797
00:29:10.000 --> 00:29:11.960
ratchet the dose there on the right side,

798
00:29:11.960 --> 00:29:13.960
and then you pinch an inch in your skin

799
00:29:13.960 --> 00:29:16.080
and then push it up against it'll auto-deploy.

800
00:29:16.080 --> 00:29:17.320
And so there's nothing that you need to do.

801
00:29:17.320 --> 00:29:19.960
You don't have to learn how to drop medication and inject.

802
00:29:19.960 --> 00:29:22.920
Whenever you're administering peptides at home,

803
00:29:22.920 --> 00:29:24.880
especially for patients that have obtained them

804
00:29:24.880 --> 00:29:26.520
from research use only markets,

805
00:29:26.520 --> 00:29:28.320
they usually come in just little vials

806
00:29:28.320 --> 00:29:30.760
that need to be drawn up with a needle, okay?

807
00:29:30.760 --> 00:29:34.440
Now, the benefit of that is that you can do custom dosing,

808
00:29:34.440 --> 00:29:35.280
all right?

809
00:29:35.280 --> 00:29:36.120
But the drawback is, is that, well,

810
00:29:36.120 --> 00:29:37.760
you have to know how to calculate that

811
00:29:37.760 --> 00:29:38.840
and put it together.

812
00:29:38.920 --> 00:29:42.280
This may be the most controversial thing

813
00:29:42.280 --> 00:29:43.640
we have on this table.

814
00:29:43.640 --> 00:29:45.600
And by pharma's estimate,

815
00:29:45.600 --> 00:29:47.160
it might be the most dangerous thing

816
00:29:47.160 --> 00:29:48.640
to their entire business model.

817
00:29:48.640 --> 00:29:51.200
Because this is tersepotide,

818
00:29:51.200 --> 00:29:53.600
the exact same thing that you had in that pen.

819
00:29:53.600 --> 00:29:58.040
But this is made by a high quality 503A compounding pharmacy.

820
00:29:58.040 --> 00:30:02.800
And the reason why this is so controversial right now

821
00:30:02.800 --> 00:30:05.600
is because it offers an incredible amount of flexibility

822
00:30:05.600 --> 00:30:08.120
because what you have in your hand there is very standardized

823
00:30:08.120 --> 00:30:09.800
and you administer it once a week

824
00:30:09.800 --> 00:30:11.040
because that's what's approved by interest.

825
00:30:11.040 --> 00:30:12.680
This is like the exact thing everyone's been talking about.

826
00:30:12.680 --> 00:30:13.920
Exactly, yeah.

827
00:30:13.920 --> 00:30:17.240
But think of that as paint by numbers, okay?

828
00:30:17.240 --> 00:30:19.800
You are, this section is this color,

829
00:30:19.800 --> 00:30:21.600
this section is that color, all right?

830
00:30:21.600 --> 00:30:24.560
Think of this as the thing you've got in your hand.

831
00:30:24.560 --> 00:30:27.720
Right now, yeah, exactly just a vial of tersepotide

832
00:30:27.720 --> 00:30:31.160
as being having infinite permutations and dosing ability

833
00:30:31.160 --> 00:30:33.640
because you can draw this up with a small syringe

834
00:30:33.640 --> 00:30:34.600
and do micro dosing.

835
00:30:34.600 --> 00:30:36.760
So instead of one large dose once a week

836
00:30:36.760 --> 00:30:38.640
because what many patients will experience

837
00:30:38.640 --> 00:30:41.280
is they'll have a return of their hunger by the end of the week

838
00:30:41.280 --> 00:30:43.120
and they end up losing ground.

839
00:30:43.120 --> 00:30:45.960
You can actually instead of doing a full dose once a week,

840
00:30:45.960 --> 00:30:48.680
you could do multiple mini doses throughout the week

841
00:30:48.680 --> 00:30:50.200
with this formulation

842
00:30:50.200 --> 00:30:52.800
and with this presentation of the medication, all right?

843
00:30:52.800 --> 00:30:55.120
But the challenge is that that is the benefit

844
00:30:55.120 --> 00:30:57.800
that allows this to be compounded by compounding pharmacies

845
00:30:57.800 --> 00:31:01.560
because they're able to provide something that is similar

846
00:31:01.560 --> 00:31:02.880
to what's in your hand, all right?

847
00:31:02.880 --> 00:31:04.880
But it offers more flexibility

848
00:31:04.880 --> 00:31:07.080
that may be the right choice for some patients.

849
00:31:07.080 --> 00:31:10.360
So personalization of medicine, okay?

850
00:31:10.360 --> 00:31:13.640
But the challenge is that if you spend however much money

851
00:31:13.640 --> 00:31:15.960
on this, you're not giving it to Lily.

852
00:31:15.960 --> 00:31:19.200
And so as a result, we have seen an unprecedented crackdown

853
00:31:19.200 --> 00:31:21.840
in the United States from the FDA

854
00:31:21.840 --> 00:31:24.360
and trying to shut down compounding pharmacies

855
00:31:24.360 --> 00:31:27.480
and prevent them from making these medications

856
00:31:27.480 --> 00:31:30.880
even though that ability to customize the fact

857
00:31:30.880 --> 00:31:34.200
that this is not an exact copy of what's in your hand right now

858
00:31:34.200 --> 00:31:36.760
should protect it under current legislation.

859
00:31:36.760 --> 00:31:40.440
But there is now enough pressure from the powers that be

860
00:31:40.440 --> 00:31:44.400
and from lobbyists, from both Lily and Novo Nordisk

861
00:31:44.400 --> 00:31:47.840
that which are the two companies that make the GLP1 medications

862
00:31:47.840 --> 00:31:51.400
that we're seeing Marty Macri, the FDA commissioner,

863
00:31:51.400 --> 00:31:53.920
has now tweeted more about cracking down

864
00:31:53.920 --> 00:31:56.000
on compounded GLP1 medications

865
00:31:56.000 --> 00:31:58.200
than he's tweeted about diabetes or heart disease

866
00:31:58.200 --> 00:31:59.800
in his entire time in office.

867
00:31:59.800 --> 00:32:02.000
And just so I understand, I want to play this back to you

868
00:32:02.000 --> 00:32:04.160
to make sure I understand, sure.

869
00:32:04.160 --> 00:32:08.880
In my hand here, I have trizapotite on my left.

870
00:32:08.880 --> 00:32:10.280
Yep, and this is made by Lily,

871
00:32:10.280 --> 00:32:12.760
which is a corporate company who has patented it

872
00:32:12.760 --> 00:32:14.080
so they can make lots of money from it.

873
00:32:14.080 --> 00:32:14.920
Right.

874
00:32:14.920 --> 00:32:18.000
In my right hand, I have trizapotite.

875
00:32:18.000 --> 00:32:19.880
Trizapotite with niacinamide.

876
00:32:19.880 --> 00:32:21.320
With niacinamide.

877
00:32:21.320 --> 00:32:22.160
Yep.

878
00:32:22.160 --> 00:32:23.560
And this is not patentable.

879
00:32:23.560 --> 00:32:27.960
So Lily has a patent on the trizapotite molecule

880
00:32:27.960 --> 00:32:29.640
in that formulation in your hand.

881
00:32:29.640 --> 00:32:30.640
Okay.

882
00:32:30.640 --> 00:32:33.840
And if anyone violates a patent,

883
00:32:33.840 --> 00:32:38.200
that can be pursued in US court, patent law, right?

884
00:32:38.200 --> 00:32:42.320
But what's interesting is that Lily and Novo Nordisk

885
00:32:42.320 --> 00:32:44.520
know that that's different in your right hand.

886
00:32:44.520 --> 00:32:45.640
It doesn't look the same.

887
00:32:45.640 --> 00:32:47.440
You can dose it differently.

888
00:32:47.440 --> 00:32:50.000
And they know that if they were going to fight that in court,

889
00:32:50.000 --> 00:32:52.840
it would cost a lot of money and take a lot of time.

890
00:32:52.840 --> 00:32:55.040
So you know, it's a lot easier calling your friend

891
00:32:55.040 --> 00:32:57.320
at the FDA and getting him to step on the competition

892
00:32:57.320 --> 00:32:58.440
so you don't have to.

893
00:32:58.480 --> 00:33:01.200
And then who's paying for that enforcement?

894
00:33:01.200 --> 00:33:05.720
It's not the lawyers that the pharma company is paying for.

895
00:33:05.720 --> 00:33:08.440
It's the taxpayer paying for the FDA through taxes.

896
00:33:08.440 --> 00:33:10.840
And you seem to imply that this was actually better

897
00:33:10.840 --> 00:33:13.040
because you could take it in a more flexible dose.

898
00:33:13.040 --> 00:33:14.120
You could take a little bit a lot.

899
00:33:14.120 --> 00:33:15.000
You can take it when you want.

900
00:33:15.000 --> 00:33:17.440
Whereas this is kind of once a week.

901
00:33:17.440 --> 00:33:19.440
Well, I mean, you know, what is better, right?

902
00:33:19.440 --> 00:33:22.120
So I like this option for many of my patients

903
00:33:22.120 --> 00:33:23.760
because it's flexible, all right?

904
00:33:23.760 --> 00:33:26.120
So that is something that works for most patients, all right?

905
00:33:26.120 --> 00:33:29.080
But then again, this works great for patients too.

906
00:33:29.080 --> 00:33:32.520
But what you want is you want an ecosystem where you have choice

907
00:33:32.520 --> 00:33:34.920
so you can make the right choice for the right patient.

908
00:33:34.920 --> 00:33:37.520
For a lot of patients, they're going to do exceedingly well

909
00:33:37.520 --> 00:33:40.120
on this and there's so much data to support that.

910
00:33:40.120 --> 00:33:43.240
But I also have a lot of patients who get really ill

911
00:33:43.240 --> 00:33:47.560
after they do a large dose of Mondarro or of GLP1 men.

912
00:33:47.560 --> 00:33:50.160
And if we take that same dose and we just cut it

913
00:33:50.160 --> 00:33:51.360
into multiple doses within a week,

914
00:33:51.360 --> 00:33:53.480
we can avoid those side effects.

915
00:33:53.480 --> 00:33:55.440
So you've told me that these peptides we have on the table

916
00:33:55.440 --> 00:33:57.920
in front of us can improve your skin, weight loss,

917
00:33:57.920 --> 00:34:01.000
muscle, energy, chronic illnesses.

918
00:34:01.000 --> 00:34:03.520
You talked about the cognitive upsides

919
00:34:03.520 --> 00:34:04.920
and you talk about it very passionately.

920
00:34:04.920 --> 00:34:05.760
Yeah.

921
00:34:05.760 --> 00:34:09.600
So one should ask you, presumably you're taking some peptides.

922
00:34:09.600 --> 00:34:10.280
I am.

923
00:34:10.280 --> 00:34:11.520
Yeah. So what ones do you take?

924
00:34:11.520 --> 00:34:14.320
So I will tell you that as of right now,

925
00:34:14.320 --> 00:34:18.080
the only peptide I'm taking is a small dose of therasaphythide,

926
00:34:18.080 --> 00:34:19.440
which is the one we were just talking about.

927
00:34:19.440 --> 00:34:19.940
Yeah.

928
00:34:19.940 --> 00:34:23.280
Because back a couple of months ago,

929
00:34:23.280 --> 00:34:27.080
I was probably close to about 240 or so.

930
00:34:27.080 --> 00:34:28.720
And I was into powerlifting.

931
00:34:28.720 --> 00:34:29.560
I still am.

932
00:34:29.560 --> 00:34:32.760
But it's really great to be able to deadlift 500 pounds.

933
00:34:32.760 --> 00:34:34.960
But then stairs become really hard when you're trying

934
00:34:34.960 --> 00:34:35.800
to walk up.

935
00:34:35.800 --> 00:34:36.720
And I don't know.

936
00:34:36.720 --> 00:34:39.160
I kind of like being able to not take a break

937
00:34:39.160 --> 00:34:40.840
after two or three flights of stairs.

938
00:34:40.840 --> 00:34:42.760
And so I was like, OK, all right, longevity

939
00:34:42.760 --> 00:34:43.760
is a priority of mine.

940
00:34:43.760 --> 00:34:45.120
I'm going to slim down a little bit.

941
00:34:45.120 --> 00:34:46.760
I'm like, let me just try this for a little bit.

942
00:34:46.760 --> 00:34:48.920
And what I found is that it is incredibly potent

943
00:34:48.920 --> 00:34:51.880
and at a very low dose, very, very tolerable.

944
00:34:51.880 --> 00:34:53.520
Why didn't you take some of the others?

945
00:34:53.520 --> 00:34:55.440
Honestly, because right now, there

946
00:34:55.440 --> 00:34:57.920
is not a legal framework for me to obtain them.

947
00:34:57.920 --> 00:35:00.040
And the truth is, is that I want

948
00:35:00.040 --> 00:35:01.680
to be an example for my patients.

949
00:35:01.680 --> 00:35:04.040
And that's why I'm out here advocating

950
00:35:04.040 --> 00:35:05.920
that we get access to these peptides

951
00:35:05.920 --> 00:35:08.200
in a legal, safe way again, all right?

952
00:35:08.200 --> 00:35:10.680
And because it's the best thing for everyone.

953
00:35:10.680 --> 00:35:14.240
If they were legal, which ones might you consider?

954
00:35:14.240 --> 00:35:15.640
Oh, man, I would tell you this.

955
00:35:15.640 --> 00:35:18.360
As some, like, I don't know how old you are, Stephen.

956
00:35:18.360 --> 00:35:19.200
But I might be 33.

957
00:35:19.200 --> 00:35:19.960
33.

958
00:35:19.960 --> 00:35:20.560
God bless you.

959
00:35:20.560 --> 00:35:23.360
I will tell you, once you get over 35, man, that is brutal.

960
00:35:23.360 --> 00:35:25.040
I sleep on my neck in a wrong way,

961
00:35:25.040 --> 00:35:27.760
and I need like a frickin' brace for like two weeks.

962
00:35:27.760 --> 00:35:30.600
And so if someone who spends a lot of time in the gym,

963
00:35:30.600 --> 00:35:32.400
working out, like you start to accumulate

964
00:35:32.400 --> 00:35:33.680
all these little aches and pains.

965
00:35:33.680 --> 00:35:35.520
And so the idea of, for example,

966
00:35:35.520 --> 00:35:38.120
I have a very finicky right shoulder.

967
00:35:38.120 --> 00:35:40.760
If I try to do a really heavy bench

968
00:35:40.760 --> 00:35:42.720
and I haven't warmed up, I can tweak this.

969
00:35:42.720 --> 00:35:45.280
And it takes me out of the fight for at least a month, okay?

970
00:35:45.280 --> 00:35:46.760
And I have to do other things.

971
00:35:46.760 --> 00:35:48.920
I would have killed at various points in time

972
00:35:48.960 --> 00:35:53.080
over the past two years to have had BPC and TB500

973
00:35:53.080 --> 00:35:55.920
to hopefully speed that sort of healing, all right?

974
00:35:55.920 --> 00:35:59.800
Also, for example, I suffer from really bad rosacea.

975
00:35:59.800 --> 00:36:01.080
It flares constantly.

976
00:36:01.080 --> 00:36:01.920
What's that?

977
00:36:01.920 --> 00:36:03.400
So just redness of the face.

978
00:36:03.400 --> 00:36:04.240
Okay.

979
00:36:04.240 --> 00:36:05.920
That, you know, it makes me look like I'm sunburned.

980
00:36:05.920 --> 00:36:08.040
And then I come in on the office on like a Tuesday

981
00:36:08.040 --> 00:36:09.440
and then my staff's like, oh my gosh,

982
00:36:09.440 --> 00:36:10.880
you go out in the yard and do some work this week.

983
00:36:10.880 --> 00:36:12.800
I'm like, this is just my face.

984
00:36:12.800 --> 00:36:15.120
You know, for example, that's something that a lot of people

985
00:36:15.120 --> 00:36:18.360
have reported benefits from GHKCU from.

986
00:36:18.360 --> 00:36:20.880
So again, another compound, another peptide

987
00:36:20.880 --> 00:36:23.240
that could be beneficial for a patient like myself.

988
00:36:23.240 --> 00:36:25.640
What about muscle mass and muscle?

989
00:36:25.640 --> 00:36:26.480
Yeah.

990
00:36:26.480 --> 00:36:29.360
So that is an interesting misnomer

991
00:36:29.360 --> 00:36:31.720
because that has been a common selling point

992
00:36:31.720 --> 00:36:33.120
that you'll see on social media.

993
00:36:33.120 --> 00:36:36.560
But as of right now, the only peptide

994
00:36:36.560 --> 00:36:38.760
that you might construe that way

995
00:36:38.760 --> 00:36:43.760
would be this guy right here in my hand, IGF1LR3, okay?

996
00:36:44.000 --> 00:36:46.840
Now, IGF1LR3 is basically

997
00:36:46.840 --> 00:36:49.520
the longer-lasting version of IGF1,

998
00:36:49.520 --> 00:36:52.360
which is the downstream effect of growth hormone.

999
00:36:52.360 --> 00:36:54.320
I'm sure you've heard of bodybuilders taking growth hormone

1000
00:36:54.320 --> 00:36:56.680
to increase size and, you know, lose fat.

1001
00:36:56.680 --> 00:37:00.760
In higher doses, it can help contribute to muscle mass, right?

1002
00:37:00.760 --> 00:37:04.920
But truthfully, if you're trying to gain significant muscle mass,

1003
00:37:04.920 --> 00:37:06.680
this is not the way to do it.

1004
00:37:06.680 --> 00:37:09.680
And so the right now, one of the things

1005
00:37:09.680 --> 00:37:11.640
that peptides can't do for you

1006
00:37:11.640 --> 00:37:14.600
is independently put on significant amounts of lean mass.

1007
00:37:14.600 --> 00:37:15.680
You still have to get to the gym.

1008
00:37:15.680 --> 00:37:17.200
You still have to go to the gym, believe it or not.

1009
00:37:17.200 --> 00:37:18.040
And guess what?

1010
00:37:18.040 --> 00:37:19.040
Well, that seemed to be the podcast.

1011
00:37:19.040 --> 00:37:19.880
Yeah.

1012
00:37:19.880 --> 00:37:21.800
I'll tell you, but something that blows my mind

1013
00:37:21.800 --> 00:37:23.080
is that I have so many patients

1014
00:37:23.080 --> 00:37:25.160
that think that they can just take testosterone

1015
00:37:25.160 --> 00:37:26.440
and just put on muscle naturally.

1016
00:37:26.440 --> 00:37:27.760
And it doesn't work that way.

1017
00:37:27.760 --> 00:37:29.120
You might get a tiny little bit,

1018
00:37:29.120 --> 00:37:30.560
but you still have to have stimulus.

1019
00:37:30.560 --> 00:37:31.440
You still have to get in the gym.

1020
00:37:31.440 --> 00:37:32.880
You still have to put the work in.

1021
00:37:32.880 --> 00:37:35.040
And so I tell patients that I am not a replacement

1022
00:37:35.040 --> 00:37:36.160
for a personal trainer.

1023
00:37:36.160 --> 00:37:37.160
I am your doctor.

1024
00:37:37.160 --> 00:37:38.640
You also need your personal trainer.

1025
00:37:38.640 --> 00:37:40.480
And most of you need a nutritionist, man.

1026
00:37:40.480 --> 00:37:42.640
And so I'm lucky to work with some great people

1027
00:37:42.640 --> 00:37:44.640
in the community who partner with me on that.

1028
00:37:44.640 --> 00:37:46.400
But it's a full court press

1029
00:37:46.400 --> 00:37:49.440
when you're trying to get people to live the highest quality life.

1030
00:37:49.440 --> 00:37:51.320
What about some of these metabolic disorders

1031
00:37:51.320 --> 00:37:54.160
and diseases in terms of insulin resistance?

1032
00:37:54.160 --> 00:37:55.600
People on the diet of the CIO,

1033
00:37:55.600 --> 00:37:58.320
the audience are very interested to learn about insulin.

1034
00:37:58.320 --> 00:37:59.520
I see that a lot in the comments section

1035
00:37:59.520 --> 00:38:00.640
and a lot of the data.

1036
00:38:00.640 --> 00:38:01.480
Yeah.

1037
00:38:01.480 --> 00:38:02.720
So how can if someone's struggling

1038
00:38:02.720 --> 00:38:04.960
with their insulin levels or their glucose response,

1039
00:38:04.960 --> 00:38:06.600
how does these peptides help?

1040
00:38:06.600 --> 00:38:08.480
Honestly, the best peptides for that right now

1041
00:38:08.480 --> 00:38:11.000
are the GLP1 drugs, hands down.

1042
00:38:11.000 --> 00:38:13.320
Because what you're doing is you are slowing

1043
00:38:13.320 --> 00:38:14.160
the gastric emptying.

1044
00:38:14.160 --> 00:38:17.520
And so you have a slower absorption

1045
00:38:17.520 --> 00:38:19.160
of that bolsa food that you've eaten.

1046
00:38:19.160 --> 00:38:20.840
So your glucose doesn't spike.

1047
00:38:20.840 --> 00:38:22.240
And so as a result,

1048
00:38:22.240 --> 00:38:25.120
that increases insulin sensitivity significantly.

1049
00:38:25.120 --> 00:38:26.920
Now, again, you have to be careful

1050
00:38:26.920 --> 00:38:28.480
about what peptides you're using for what?

1051
00:38:28.480 --> 00:38:31.760
A lot of these peptides that boost growth hormone

1052
00:38:31.760 --> 00:38:34.200
and boost, let's say IGF1,

1053
00:38:34.200 --> 00:38:37.280
those can actually increase serum glucose.

1054
00:38:37.280 --> 00:38:39.000
And that may not be what you want

1055
00:38:39.000 --> 00:38:40.520
if you are someone that is trying

1056
00:38:40.520 --> 00:38:42.600
to work on your insulin sensitivity.

1057
00:38:42.600 --> 00:38:45.320
And to any of these peptides come as like creams

1058
00:38:45.320 --> 00:38:47.760
or as pills or anything like that.

1059
00:38:47.760 --> 00:38:48.800
If you look online,

1060
00:38:48.800 --> 00:38:50.320
you can probably find a version of everything.

1061
00:38:50.320 --> 00:38:53.640
But if we're talking about actual legitimate formulations,

1062
00:38:53.640 --> 00:38:56.360
the best example of a topical cream

1063
00:38:56.360 --> 00:38:57.960
is going to be GHKCU.

1064
00:38:57.960 --> 00:39:01.040
And this is interesting because this is a copper tripeptide

1065
00:39:01.040 --> 00:39:03.840
that has been found to decrease

1066
00:39:03.840 --> 00:39:06.480
in expression and concentration as we age.

1067
00:39:06.480 --> 00:39:08.320
But when it is applied topically,

1068
00:39:08.320 --> 00:39:09.960
it's highly effectively,

1069
00:39:09.960 --> 00:39:12.480
so putting on a cream on your face, all right?

1070
00:39:12.520 --> 00:39:14.600
It's been found to be extremely beneficial

1071
00:39:14.600 --> 00:39:17.080
in regenerating the quality of skin.

1072
00:39:17.080 --> 00:39:18.840
So complexion, all right?

1073
00:39:18.840 --> 00:39:21.360
Increasing the amount of collagen and elastin,

1074
00:39:21.360 --> 00:39:24.400
the things that we need to keep our faces taught and youthful,

1075
00:39:24.400 --> 00:39:26.360
the things that people will pay lots of money

1076
00:39:26.360 --> 00:39:28.000
to go get laser to get improvements.

1077
00:39:28.000 --> 00:39:29.720
Not that it's a replacement for that,

1078
00:39:29.720 --> 00:39:32.640
but that's a topical form that believe it or not,

1079
00:39:32.640 --> 00:39:33.760
you could go out and buy today

1080
00:39:33.760 --> 00:39:37.600
because topical GHKCU is regulated very differently

1081
00:39:37.600 --> 00:39:39.320
than the injectable form.

1082
00:39:39.320 --> 00:39:41.320
Is it expensive usually?

1083
00:39:41.320 --> 00:39:42.280
You know, growing up, I thought

1084
00:39:42.280 --> 00:39:45.000
all these sort of anti-aging creams were bullshit.

1085
00:39:45.000 --> 00:39:47.880
But you're telling me that this has actually been associated

1086
00:39:47.880 --> 00:39:50.320
with improving signs of aging.

1087
00:39:50.320 --> 00:39:51.160
I will tell you this,

1088
00:39:51.160 --> 00:39:53.600
when I was going through college and medical school,

1089
00:39:53.600 --> 00:39:55.040
I was the biggest skeptic.

1090
00:39:55.040 --> 00:39:58.360
Like I did not believe any of the health or wellness claims

1091
00:39:58.360 --> 00:39:59.720
that we saw coming out at the time.

1092
00:39:59.720 --> 00:40:01.200
And again, you know, that was at a time

1093
00:40:01.200 --> 00:40:02.720
where we were getting bombarded with stuff

1094
00:40:02.720 --> 00:40:04.840
about the acne's diet and this out of the other.

1095
00:40:04.840 --> 00:40:05.920
But then all of a sudden,

1096
00:40:05.920 --> 00:40:07.720
you start having patients come back to you

1097
00:40:07.720 --> 00:40:09.120
and they're testifying as the benefits

1098
00:40:09.120 --> 00:40:10.200
they've seen from these things.

1099
00:40:10.200 --> 00:40:12.240
And you start to actually look at the biochemistry behind them.

1100
00:40:12.240 --> 00:40:14.880
You're like, there's a lot of science backing this up.

1101
00:40:14.880 --> 00:40:16.720
This isn't just mumbo jumbo.

1102
00:40:16.720 --> 00:40:18.400
And so believe it or not,

1103
00:40:18.400 --> 00:40:21.880
yeah, there are creams that can slow the process of aging,

1104
00:40:21.880 --> 00:40:23.000
at least from a visual standpoint,

1105
00:40:23.000 --> 00:40:24.280
when it comes to your skin.

1106
00:40:24.280 --> 00:40:26.720
I have yet to figure out anything that, you know,

1107
00:40:26.720 --> 00:40:29.120
makes me as energetic as I was in my early 20s,

1108
00:40:29.120 --> 00:40:30.440
but you know, I'm working on it.

1109
00:40:30.440 --> 00:40:33.080
But on that point of energy and cognition,

1110
00:40:33.080 --> 00:40:35.520
if I wanted to become a better pollcaster, yeah.

1111
00:40:35.520 --> 00:40:36.720
And you know, I say here sometimes,

1112
00:40:36.720 --> 00:40:37.800
sometimes we do tune a day,

1113
00:40:37.800 --> 00:40:39.200
which means I might see it for eight hours.

1114
00:40:39.640 --> 00:40:41.360
I think a couple of times you've done three in a day.

1115
00:40:41.360 --> 00:40:42.200
That's brutal.

1116
00:40:42.200 --> 00:40:43.240
Which is 12 hours of recording.

1117
00:40:43.240 --> 00:40:44.560
Yeah. But what would you recommend

1118
00:40:44.560 --> 00:40:46.480
if I was trying to improve my cognitive performance?

1119
00:40:46.480 --> 00:40:47.840
So again, as a physician,

1120
00:40:47.840 --> 00:40:49.080
it likes keeping my license.

1121
00:40:49.080 --> 00:40:50.840
I would say necessarily recommend,

1122
00:40:50.840 --> 00:40:53.960
but I would say if we're looking at how these medications

1123
00:40:53.960 --> 00:40:57.320
have been used and potentially one that may be legal again,

1124
00:40:57.320 --> 00:40:59.640
coming this July pending what the FDA says,

1125
00:40:59.640 --> 00:41:01.080
intranasal CMax.

1126
00:41:01.080 --> 00:41:03.280
And this was one that was originally studied

1127
00:41:03.280 --> 00:41:06.400
actually in Russia many years ago.

1128
00:41:06.400 --> 00:41:10.480
And what they found is that this seven amino acid peptide

1129
00:41:10.480 --> 00:41:14.120
when it was administered after a TBI,

1130
00:41:14.120 --> 00:41:17.120
so a traumatic brain injury or acute injury

1131
00:41:17.120 --> 00:41:19.640
that patients tended to bounce back faster.

1132
00:41:19.640 --> 00:41:23.000
Also, they saw evidence of it improving outcomes after stroke.

1133
00:41:23.000 --> 00:41:26.280
And it also seems to upregulate the same sort of factors

1134
00:41:26.280 --> 00:41:28.200
that help with cognition

1135
00:41:28.200 --> 00:41:31.840
and with connecting sentences and bits of data in your brain.

1136
00:41:31.840 --> 00:41:34.240
And so it's also one of the interestingly enough,

1137
00:41:34.240 --> 00:41:37.320
one of the ones that is available intranasally

1138
00:41:37.320 --> 00:41:38.880
because it goes through the mucus membranes

1139
00:41:38.880 --> 00:41:40.440
and gets right where you need it.

1140
00:41:40.440 --> 00:41:43.080
And so that's gonna be a really, really fascinating

1141
00:41:43.080 --> 00:41:44.760
compound to see back on the market.

1142
00:41:44.760 --> 00:41:47.880
And then we can actually get more data regarding efficacy

1143
00:41:47.880 --> 00:41:50.320
and across a wide population.

1144
00:41:50.320 --> 00:41:51.160
So interesting.

1145
00:41:51.160 --> 00:41:53.640
And you can even sniff that through your nose.

1146
00:41:53.640 --> 00:41:56.800
Like you would for any nasal decongestant, right?

1147
00:41:56.800 --> 00:41:58.680
And if you have allergies or something like that.

1148
00:41:58.680 --> 00:42:01.320
Also for someone like yourself, you travel a lot.

1149
00:42:01.320 --> 00:42:02.960
You're going in between different time zones.

1150
00:42:02.960 --> 00:42:04.520
You're balancing multiple obligations

1151
00:42:04.520 --> 00:42:06.000
at different odd times of the day.

1152
00:42:06.000 --> 00:42:08.800
I shudder to think what your circadian rhythm looks like,

1153
00:42:08.800 --> 00:42:09.800
my friend.

1154
00:42:09.800 --> 00:42:11.360
But that is what we have.

1155
00:42:11.360 --> 00:42:13.960
Some of these other compounds that are gonna be available for.

1156
00:42:13.960 --> 00:42:17.880
So if we look at a D-SIP, okay?

1157
00:42:17.880 --> 00:42:19.680
That has been shown to be helpful

1158
00:42:19.680 --> 00:42:22.440
with regulating your circadian rhythm, all right?

1159
00:42:22.440 --> 00:42:24.040
That is one of the ones that's gonna be approved

1160
00:42:24.040 --> 00:42:26.840
hopefully here soon again in July, right?

1161
00:42:26.840 --> 00:42:31.200
And then on top of that, you've got things like Selenck,

1162
00:42:31.200 --> 00:42:33.480
which is another one that can help calm you

1163
00:42:33.480 --> 00:42:35.840
as you're going to sleep about an hour ahead of time.

1164
00:42:35.840 --> 00:42:39.120
And again, help those deep delta wave brain waves

1165
00:42:39.120 --> 00:42:43.440
that are so restorative whenever you actually are resting.

1166
00:42:43.440 --> 00:42:45.320
Where will we be able to buy these

1167
00:42:45.320 --> 00:42:47.280
when and if they are legalized?

1168
00:42:47.280 --> 00:42:52.440
So from 503A compounders here in the United States

1169
00:42:52.440 --> 00:42:54.600
with a prescription from a physician.

1170
00:42:54.600 --> 00:42:55.760
So you still need a prescription.

1171
00:42:55.760 --> 00:42:58.200
You still need a prescription, correct?

1172
00:42:58.200 --> 00:42:59.280
It can be quite crazy world

1173
00:42:59.280 --> 00:43:02.800
when everybody is gonna be injecting themselves every day.

1174
00:43:02.800 --> 00:43:04.160
I mean, we're already getting to that point now

1175
00:43:04.160 --> 00:43:05.840
with a Zem pack where I've got loads of people

1176
00:43:05.840 --> 00:43:07.520
in my friendship group that are.

1177
00:43:07.520 --> 00:43:09.720
Yeah, and they're doing great.

1178
00:43:09.720 --> 00:43:10.800
Yeah, they're doing great.

1179
00:43:10.800 --> 00:43:11.640
They're doing great.

1180
00:43:11.640 --> 00:43:15.040
And that's what I like about the advent of these GLP ones

1181
00:43:15.040 --> 00:43:17.080
is they're removing the stigma of a needle.

1182
00:43:17.080 --> 00:43:19.600
And I look at some of my friends who have been on it.

1183
00:43:19.600 --> 00:43:21.480
I can't recognize them, they look awesome.

1184
00:43:21.480 --> 00:43:24.400
Are you concerned with any of them?

1185
00:43:24.400 --> 00:43:26.240
You know, I've got a couple of friends in my circle

1186
00:43:26.240 --> 00:43:27.920
where I'm a little bit concerned.

1187
00:43:27.920 --> 00:43:29.600
I don't even know if I should be concerned,

1188
00:43:29.600 --> 00:43:32.120
but it's just when you see someone you know change

1189
00:43:32.120 --> 00:43:33.800
so dramatically, so quickly.

1190
00:43:33.800 --> 00:43:35.440
Yeah, I think there's something in us

1191
00:43:35.440 --> 00:43:37.200
which is something pretty historic in us

1192
00:43:37.200 --> 00:43:38.560
which goes, oh my god, there's a problem.

1193
00:43:38.560 --> 00:43:40.760
Yeah, one thing I am concerned about

1194
00:43:40.760 --> 00:43:44.040
is the rapid weight loss with GLP1 medications.

1195
00:43:44.040 --> 00:43:45.960
Because the problem is that when you go

1196
00:43:45.960 --> 00:43:47.920
into such a radical caloric deficit,

1197
00:43:47.920 --> 00:43:51.400
your body goes into catabolism, which is breaking down tissue.

1198
00:43:51.400 --> 00:43:53.040
And you wanna break down fat, right?

1199
00:43:53.040 --> 00:43:54.600
But your body isn't that judicious.

1200
00:43:54.600 --> 00:43:55.840
It's gonna break down muscle.

1201
00:43:56.000 --> 00:43:59.000
And muscle is the most metabolically important tissue

1202
00:43:59.000 --> 00:44:00.240
that any of us have.

1203
00:44:00.240 --> 00:44:02.840
And so if you really wanna optimize your insulin sensitivity,

1204
00:44:02.840 --> 00:44:04.520
well, you need to maintain your muscle.

1205
00:44:04.520 --> 00:44:07.600
And right now, really the only compounds that we have

1206
00:44:07.600 --> 00:44:09.280
that are really good at preserving muscle

1207
00:44:09.280 --> 00:44:11.520
with resistance training is testosterone, right?

1208
00:44:11.520 --> 00:44:13.320
But that isn't gonna be a good option

1209
00:44:13.320 --> 00:44:15.200
for our male patients that wanna get pregnant

1210
00:44:15.200 --> 00:44:17.720
because testosterone turns off fertility in men, all right?

1211
00:44:17.720 --> 00:44:20.760
It's also not a great idea for our female patients,

1212
00:44:20.760 --> 00:44:22.800
all right, depending on their age, testosterone,

1213
00:44:22.800 --> 00:44:25.440
TRT is a thing in older women,

1214
00:44:25.440 --> 00:44:26.760
menopausal won't go into that.

1215
00:44:26.760 --> 00:44:29.520
But truthfully, testosterone is not the right answer

1216
00:44:29.520 --> 00:44:30.360
for everybody.

1217
00:44:30.360 --> 00:44:34.760
And so what we are gonna see come down the pipe very soon

1218
00:44:34.760 --> 00:44:36.680
is kind of the older brother of peptides,

1219
00:44:36.680 --> 00:44:40.120
the more complex form biologics called monoclonal antibodies

1220
00:44:40.120 --> 00:44:43.080
that are specifically designed to inhibit

1221
00:44:43.080 --> 00:44:44.920
the enzymes that break down muscle.

1222
00:44:44.920 --> 00:44:47.600
So these are specifically called myostatin inhibitors.

1223
00:44:47.600 --> 00:44:49.960
There are three that are coming down the pipeline.

1224
00:44:49.960 --> 00:44:52.640
There is one called the magramab, which is owned by Lily.

1225
00:44:52.640 --> 00:44:55.120
That is going to bind to the peanut butter

1226
00:44:55.120 --> 00:44:57.880
to myostatin's jelly, which is called active in.

1227
00:44:57.880 --> 00:45:01.440
And then you have heredosmab and travogumab,

1228
00:45:01.440 --> 00:45:04.240
which are two other compounds owned

1229
00:45:04.240 --> 00:45:05.720
by different pharmaceutical company

1230
00:45:05.720 --> 00:45:07.880
that are all designed to maintain muscle

1231
00:45:07.880 --> 00:45:10.080
even in a significant caloric deficit.

1232
00:45:10.080 --> 00:45:11.280
This is getting interesting now.

1233
00:45:11.280 --> 00:45:12.120
Yeah, yeah.

1234
00:45:12.120 --> 00:45:14.440
So you're telling me I'm gonna be able to inject myself

1235
00:45:14.440 --> 00:45:16.080
with this impact to lose the fat

1236
00:45:16.080 --> 00:45:18.320
and then inject myself with something else to keep the muscle.

1237
00:45:18.320 --> 00:45:19.800
It's wild.

1238
00:45:19.800 --> 00:45:20.640
It's wild.

1239
00:45:21.640 --> 00:45:25.440
And I'll tell you one of the hardest things

1240
00:45:25.440 --> 00:45:26.680
that I'm sure you've heard being

1241
00:45:26.680 --> 00:45:29.440
on the receiving end of this is just the complexity of it.

1242
00:45:29.440 --> 00:45:31.960
And there are so many levers that are moving at once

1243
00:45:31.960 --> 00:45:35.120
and trying to get your head around it and balance it all.

1244
00:45:35.120 --> 00:45:38.840
It requires nuance and it requires a thoughtful discussion

1245
00:45:38.840 --> 00:45:42.000
with your doctor who's well-educated on them.

1246
00:45:42.000 --> 00:45:44.280
And that's one of the challenges is that

1247
00:45:44.280 --> 00:45:46.200
there isn't broad, great education

1248
00:45:46.200 --> 00:45:48.800
on these products right now in the medical space.

1249
00:45:48.840 --> 00:45:51.080
And so that's something that I'm very passionate about

1250
00:45:51.080 --> 00:45:54.200
is improving education across my colleagues

1251
00:45:54.200 --> 00:45:56.320
so that they're not afraid of these anymore.

1252
00:45:56.320 --> 00:45:57.440
What'd you say to people that are listening

1253
00:45:57.440 --> 00:45:58.440
to this now, you're fucking out.

1254
00:45:58.440 --> 00:46:01.480
Why don't you just like eat your greens and go to the gym?

1255
00:46:01.480 --> 00:46:02.320
Yeah.

1256
00:46:02.320 --> 00:46:03.720
And just be more human and you'll be fine.

1257
00:46:03.720 --> 00:46:04.560
I love that.

1258
00:46:04.560 --> 00:46:07.480
I love eating your greens and going to the gym, okay?

1259
00:46:07.480 --> 00:46:10.840
But the unfortunate reality is that here in the United States,

1260
00:46:10.840 --> 00:46:13.320
it depends on what database you look at.

1261
00:46:13.320 --> 00:46:17.200
But obesity rates are estimated to be 40 to 70%.

1262
00:46:17.200 --> 00:46:20.200
Okay, whether you, depending on what BMI cut off you're using,

1263
00:46:20.200 --> 00:46:22.520
okay, BMI is not perfect, but it is what it is.

1264
00:46:22.520 --> 00:46:24.400
And so the thing is, is that, well,

1265
00:46:24.400 --> 00:46:26.160
eating greens and going to the gym

1266
00:46:26.160 --> 00:46:28.520
are not working for us as a society.

1267
00:46:28.520 --> 00:46:31.320
And we could talk about how we don't have real food anymore.

1268
00:46:31.320 --> 00:46:32.600
We have food deserts.

1269
00:46:32.600 --> 00:46:36.680
We have this colloquially dense, but nutritionally poor food.

1270
00:46:36.680 --> 00:46:39.280
I'll tell you, the most disturbing thing I see

1271
00:46:39.280 --> 00:46:41.760
as a surgeon is I'll see a patient come in the door.

1272
00:46:41.760 --> 00:46:42.960
And they're morbidly obese.

1273
00:46:42.960 --> 00:46:45.320
They're a large individual, but I have to do surgery on them.

1274
00:46:45.320 --> 00:46:46.800
But the connective tissue, the stuff

1275
00:46:46.800 --> 00:46:48.360
is made of a protein that makes them,

1276
00:46:48.360 --> 00:46:51.760
them that literally holds them together is paper, paper, thin

1277
00:46:51.760 --> 00:46:54.000
because they're eating an incredible amount of calories.

1278
00:46:54.000 --> 00:46:56.480
They're gaining fat, but they don't have any protein in their diet.

1279
00:46:56.480 --> 00:46:58.360
And that's not something that's rare.

1280
00:46:58.360 --> 00:47:00.000
I see that on a daily basis.

1281
00:47:00.000 --> 00:47:02.960
And so the truth is, is that, we're talking about this

1282
00:47:02.960 --> 00:47:05.520
from the angle of biohackers and people

1283
00:47:05.520 --> 00:47:07.240
that are super engaged in our health.

1284
00:47:07.240 --> 00:47:10.240
But the truth is, is that this is going to be able to be used

1285
00:47:10.240 --> 00:47:12.520
to help our population at large.

1286
00:47:12.520 --> 00:47:16.040
And ultimately, hopefully avoid a lot

1287
00:47:16.040 --> 00:47:17.240
of the terrible disease states

1288
00:47:17.240 --> 00:47:19.640
that we're seeing overwhelm the medical system right now.

1289
00:47:19.640 --> 00:47:22.800
How big is the peptide industry right now?

1290
00:47:22.800 --> 00:47:26.000
If we look at the top four large language models companies,

1291
00:47:26.000 --> 00:47:27.520
all right, so all the heavy hitters

1292
00:47:27.520 --> 00:47:29.400
and how much revenue they're generating,

1293
00:47:29.400 --> 00:47:34.400
it's estimated between 58 billion up to maybe 62 billion.

1294
00:47:35.320 --> 00:47:39.200
Yet the income and the revenue from just semi-gluteide

1295
00:47:39.200 --> 00:47:44.000
and tersepatide alone is going to be over 55 billion this year.

1296
00:47:44.000 --> 00:47:46.440
And so what we have is peptides

1297
00:47:46.440 --> 00:47:48.440
without even considering all of this happening

1298
00:47:48.440 --> 00:47:51.080
in the research space or the research-use-only space,

1299
00:47:51.080 --> 00:47:53.240
without even considering the peptides

1300
00:47:53.240 --> 00:47:56.040
that we'll see come from compounding pharmacies.

1301
00:47:56.040 --> 00:47:58.080
We're already approaching parity

1302
00:47:58.080 --> 00:48:01.120
with what we're seeing in AI as far as revenue goes.

1303
00:48:01.120 --> 00:48:04.440
That is the demand that we're seeing in the marketplace.

1304
00:48:04.440 --> 00:48:07.320
I run multiple companies that have multiple sales teams.

1305
00:48:07.320 --> 00:48:09.160
And one of the things as a founder of a company

1306
00:48:09.160 --> 00:48:11.360
that's often confusing is you find it hard

1307
00:48:11.360 --> 00:48:12.840
to figure out where sales are.

1308
00:48:12.840 --> 00:48:14.080
So about 10 years ago,

1309
00:48:14.080 --> 00:48:16.520
I started using pipe drive in my former company.

1310
00:48:16.520 --> 00:48:18.240
And it's also the reason why I switched over

1311
00:48:18.240 --> 00:48:19.200
all of my commercial teams

1312
00:48:19.200 --> 00:48:20.960
in my current media company called steven.com

1313
00:48:20.960 --> 00:48:22.280
to use pipe drive as well.

1314
00:48:22.280 --> 00:48:23.680
Not only do they sponsor this show,

1315
00:48:23.680 --> 00:48:25.240
but they've been an incredibly effective way

1316
00:48:25.240 --> 00:48:27.040
of scaling our sales engine over the years.

1317
00:48:27.040 --> 00:48:30.200
Pipedrive is an easy to use intelligence CRM.

1318
00:48:30.200 --> 00:48:31.560
And at its very core,

1319
00:48:31.560 --> 00:48:35.520
it makes your sales process visible through one dashboard,

1320
00:48:35.520 --> 00:48:38.080
a visual pipeline showing every deal,

1321
00:48:38.080 --> 00:48:40.440
what stage it's in, what needs to happen next,

1322
00:48:40.440 --> 00:48:42.880
and it's all in real time with no delay.

1323
00:48:42.880 --> 00:48:45.360
It doesn't magically close the deal for you, of course,

1324
00:48:45.360 --> 00:48:48.080
but it does replace complexity with clarity.

1325
00:48:48.080 --> 00:48:50.520
If you want to join over 100,000 companies

1326
00:48:50.520 --> 00:48:51.720
already using pipe drive,

1327
00:48:51.720 --> 00:48:54.160
you can use my link for a 30 day free trial

1328
00:48:54.160 --> 00:48:55.960
with no credit card payment needed.

1329
00:48:55.960 --> 00:48:59.720
Head to pipedrive.com slash CEO to get started.

1330
00:48:59.720 --> 00:49:03.600
That's pipe drive.com slash CEO.

1331
00:49:03.600 --> 00:49:05.600
I'll see you over there.

1332
00:49:05.600 --> 00:49:07.840
When your patients come and see you, Dr Alex,

1333
00:49:08.120 --> 00:49:10.960
what are they asking you most frequently

1334
00:49:10.960 --> 00:49:12.320
as it relates to peptides?

1335
00:49:12.320 --> 00:49:14.840
What do I like to talk three questions you get asked the most?

1336
00:49:14.840 --> 00:49:17.120
The first thing I get asked is,

1337
00:49:17.120 --> 00:49:18.520
what peptides do I need?

1338
00:49:18.520 --> 00:49:20.000
And then I just look at them and I'm like,

1339
00:49:20.000 --> 00:49:21.680
well, what's your problem?

1340
00:49:21.680 --> 00:49:23.040
What's bothering you?

1341
00:49:23.040 --> 00:49:24.240
And what did they say?

1342
00:49:24.240 --> 00:49:26.560
And then they'll come in and they'll start talking about,

1343
00:49:26.560 --> 00:49:28.440
no, energy, sex drive and that sort of things.

1344
00:49:28.440 --> 00:49:30.200
And I'm like, okay, if that's it,

1345
00:49:30.200 --> 00:49:32.480
well, we need to check your testosterone levels, brother.

1346
00:49:32.480 --> 00:49:35.720
So instead of looking for peptides, right?

1347
00:49:35.720 --> 00:49:37.760
You don't walk into a home depot or a loas,

1348
00:49:37.760 --> 00:49:39.080
like, what tools do I need?

1349
00:49:39.080 --> 00:49:40.880
And you're like, what are you trying to do, right?

1350
00:49:40.880 --> 00:49:42.400
And then you start to talk to someone there,

1351
00:49:42.400 --> 00:49:43.320
like, well, I'm trying to build this.

1352
00:49:43.320 --> 00:49:44.160
Okay, you need a saw.

1353
00:49:44.160 --> 00:49:45.400
You need a screwdriver, you need this.

1354
00:49:45.400 --> 00:49:48.080
And some of those tools might be peptides, right?

1355
00:49:48.080 --> 00:49:49.480
But some of them may be hormones.

1356
00:49:49.480 --> 00:49:51.000
Some of it may be diet and exercise.

1357
00:49:51.000 --> 00:49:53.480
And so peptides are just another type of tool

1358
00:49:53.480 --> 00:49:54.320
that we can use.

1359
00:49:54.320 --> 00:49:56.160
We all want a shortcut, though, Dr.,

1360
00:49:56.160 --> 00:49:58.120
we all want a quick way to be better.

1361
00:49:58.120 --> 00:49:59.760
Yeah, and ideally not to have to do hard work.

1362
00:49:59.760 --> 00:50:00.640
That's like what most, you know,

1363
00:50:00.640 --> 00:50:01.800
the average person is looking for.

1364
00:50:01.800 --> 00:50:02.680
And we hear about these peptides.

1365
00:50:02.680 --> 00:50:03.920
We hear other people are taking them.

1366
00:50:03.920 --> 00:50:06.520
We hear the fantastic results and skin, hair, muscle.

1367
00:50:06.560 --> 00:50:08.160
And we go, what about me?

1368
00:50:08.160 --> 00:50:10.840
You know what, I tell patients, I'm like, me too, man.

1369
00:50:10.840 --> 00:50:13.080
But my alarm still went off at 4.45 this morning

1370
00:50:13.080 --> 00:50:14.920
so I can hit the gym before I made it to clinic

1371
00:50:14.920 --> 00:50:17.160
because there are no real shortcuts.

1372
00:50:17.160 --> 00:50:19.040
There are things that can help, right?

1373
00:50:19.040 --> 00:50:21.160
GLP ones are the best example of that, right?

1374
00:50:21.160 --> 00:50:22.280
Okay, this is the closest thing

1375
00:50:22.280 --> 00:50:23.600
that you'll shortcut you're going to get.

1376
00:50:23.600 --> 00:50:25.520
But the truth is, is that this isn't going to go

1377
00:50:25.520 --> 00:50:27.320
to the gym for you and it's not going to lift the weight

1378
00:50:27.320 --> 00:50:28.680
so you can maintain that muscle mass.

1379
00:50:28.680 --> 00:50:29.800
So you get the best pasta result

1380
00:50:29.800 --> 00:50:31.880
and try to hold onto your muscle while losing the fat.

1381
00:50:31.880 --> 00:50:33.840
One thing I've learned from Dana's podcast

1382
00:50:33.840 --> 00:50:35.720
that is really grown with me over time.

1383
00:50:35.720 --> 00:50:36.560
People ask me all the time,

1384
00:50:36.560 --> 00:50:38.480
like, what's the one thing you've learned from the podcast?

1385
00:50:38.480 --> 00:50:40.400
One of the answers that I've never given

1386
00:50:40.400 --> 00:50:42.760
that I'm going to give now is that I've learned

1387
00:50:42.760 --> 00:50:44.880
that there's no such thing in life as a free lunch.

1388
00:50:44.880 --> 00:50:46.920
No, absolutely not.

1389
00:50:46.920 --> 00:50:51.160
And what I mean by that is like everything is a trade-off.

1390
00:50:51.160 --> 00:50:54.640
And if you ever hear on a podcast or in any medium

1391
00:50:54.640 --> 00:50:56.880
that something has tremendous upsides,

1392
00:50:56.880 --> 00:51:00.000
the first question one should ask is, what's the trade?

1393
00:51:00.000 --> 00:51:01.560
And like just with everything, you can apply this

1394
00:51:01.560 --> 00:51:03.040
to having a relationship with a partner.

1395
00:51:03.040 --> 00:51:05.200
Huge upsides, also trade-off.

1396
00:51:05.720 --> 00:51:08.160
Yeah, kids, I love my children.

1397
00:51:08.160 --> 00:51:10.320
I've been slept in years, right?

1398
00:51:10.320 --> 00:51:12.080
This is just, this is life, right?

1399
00:51:12.080 --> 00:51:14.120
There are trade-offs and even with great tools,

1400
00:51:14.120 --> 00:51:14.960
there are trade-offs.

1401
00:51:14.960 --> 00:51:17.080
So what are the trade-offs of these peptides?

1402
00:51:17.080 --> 00:51:20.000
The biggest trade-off right now is you don't know

1403
00:51:20.000 --> 00:51:21.800
if you're even getting what you want, right?

1404
00:51:21.800 --> 00:51:25.200
Because you're ordering this from some research compound only.

1405
00:51:25.200 --> 00:51:26.480
You don't know whether or not they've gotten out

1406
00:51:26.480 --> 00:51:27.560
all they appropriate into toxins.

1407
00:51:27.560 --> 00:51:29.480
You don't know if you're getting what you actually paid for.

1408
00:51:29.480 --> 00:51:30.760
So that's the biggest thing.

1409
00:51:30.760 --> 00:51:33.320
And also the thing is that, well, all right,

1410
00:51:33.720 --> 00:51:35.720
these have a good example of, okay,

1411
00:51:35.720 --> 00:51:38.160
preventing or helping heal injury.

1412
00:51:38.160 --> 00:51:41.080
But the thing is that, well, we've got other compounds

1413
00:51:41.080 --> 00:51:43.440
over here, let's go ahead and like,

1414
00:51:43.440 --> 00:51:46.080
let's just pull Tesla Moreland as an example.

1415
00:51:46.080 --> 00:51:47.560
So this is actually interesting.

1416
00:51:47.560 --> 00:51:50.320
It's a peptide that is commercially available right now.

1417
00:51:50.320 --> 00:51:51.320
I could write this script for you,

1418
00:51:51.320 --> 00:51:53.320
you could go pick it up from CVS or Walgreens, okay?

1419
00:51:53.320 --> 00:51:55.120
This is available as a commercial product.

1420
00:51:55.120 --> 00:51:57.720
And people really like it because it'll help boost growth

1421
00:51:57.720 --> 00:51:59.400
hormone and it happens to be uniquely good

1422
00:51:59.400 --> 00:52:02.160
at stripping abdominal fat, okay, or visceral fat.

1423
00:52:02.240 --> 00:52:03.760
But the thing is, is that, you know,

1424
00:52:03.760 --> 00:52:06.160
the moment you stop taking it for a brief period of time,

1425
00:52:06.160 --> 00:52:08.080
well, if you haven't changed anything about your lifestyle,

1426
00:52:08.080 --> 00:52:09.440
you're gonna write back to where you were.

1427
00:52:09.440 --> 00:52:11.560
It's good at stripping abdominal fat, belly fat.

1428
00:52:11.560 --> 00:52:13.600
Your belly fat, this is what it's known for.

1429
00:52:13.600 --> 00:52:14.280
Yeah.

1430
00:52:14.280 --> 00:52:15.680
It's good at stripping belly fat.

1431
00:52:15.680 --> 00:52:16.920
Stripping belly fat specifically.

1432
00:52:16.920 --> 00:52:18.320
So bodybuilders actually really like it

1433
00:52:18.320 --> 00:52:20.800
for that particular application.

1434
00:52:20.800 --> 00:52:23.960
I had no idea there was a peptide for stripping belly fat.

1435
00:52:23.960 --> 00:52:25.240
There you go, man, you know?

1436
00:52:25.240 --> 00:52:26.880
And like, for example, here, we've got another one.

1437
00:52:26.880 --> 00:52:28.840
So this is Melana Tan II, right?

1438
00:52:28.840 --> 00:52:32.000
So this is a Melana cordon receptor agonist.

1439
00:52:32.000 --> 00:52:34.640
So Melana cordons this, what makes you tan, right?

1440
00:52:34.640 --> 00:52:36.720
So you could administer this, all right?

1441
00:52:36.720 --> 00:52:40.360
And it will actually end up giving you a deep tan

1442
00:52:40.360 --> 00:52:43.720
in response to just a little bit of UV sun exposure, all right?

1443
00:52:43.720 --> 00:52:45.440
Now, I know, right?

1444
00:52:45.440 --> 00:52:47.000
Listen, I've embraced my pasty whiteness,

1445
00:52:47.000 --> 00:52:50.640
so I'm not necessarily my bag, but it's real.

1446
00:52:50.640 --> 00:52:52.560
Now, again, there are some safety concerns with this

1447
00:52:52.560 --> 00:52:54.240
because again, could that potentially stimulate

1448
00:52:54.240 --> 00:52:56.240
a melanoma or something like that?

1449
00:52:56.240 --> 00:52:58.480
But this is something, again, it's a peptide

1450
00:52:58.480 --> 00:53:00.000
that gives a wildly different result

1451
00:53:00.000 --> 00:53:01.280
than Tessa Morlin, right?

1452
00:53:01.280 --> 00:53:02.600
Because it's a different time.

1453
00:53:02.600 --> 00:53:03.440
It does.

1454
00:53:03.440 --> 00:53:04.280
Yeah, it does.

1455
00:53:04.280 --> 00:53:07.600
It'll also give you some of the most impressive

1456
00:53:07.600 --> 00:53:11.120
erections you've ever had in your life, so be warned.

1457
00:53:11.120 --> 00:53:13.880
Wait, it's literally taming you into a black guy.

1458
00:53:15.880 --> 00:53:17.880
Finally, yeah, right?

1459
00:53:17.880 --> 00:53:18.720
And it's wild.

1460
00:53:18.720 --> 00:53:20.280
So there's actually, and there's even a derivative

1461
00:53:20.280 --> 00:53:25.080
of Melana Tan II called PT-141, Bremelana Tide,

1462
00:53:25.080 --> 00:53:27.720
that is a commercial product right now

1463
00:53:27.720 --> 00:53:30.080
that you can write as a prescription, okay?

1464
00:53:30.080 --> 00:53:32.200
But that doesn't have the tanning benefit,

1465
00:53:32.200 --> 00:53:34.840
but has the sexual benefits.

1466
00:53:34.840 --> 00:53:35.440
Oh, wow.

1467
00:53:35.440 --> 00:53:36.600
Yeah.

1468
00:53:36.600 --> 00:53:37.680
Keep those ones over here.

1469
00:53:37.680 --> 00:53:38.520
We have to talk about this.

1470
00:53:38.520 --> 00:53:41.000
Another really interesting thing that phenomenon

1471
00:53:41.000 --> 00:53:42.640
that we've seen, right, is that now we've got

1472
00:53:42.640 --> 00:53:44.800
all of these companies that are making these research

1473
00:53:44.800 --> 00:53:45.920
use only compounds, right?

1474
00:53:45.920 --> 00:53:47.920
It used to be that you would have a compound

1475
00:53:47.920 --> 00:53:49.800
that's in drug development, and you're seeing all

1476
00:53:49.800 --> 00:53:51.240
the advertisements for it.

1477
00:53:51.240 --> 00:53:52.680
Maybe if you follow these sorts of things,

1478
00:53:52.680 --> 00:53:53.720
like I do because I'm a nerd, right?

1479
00:53:53.720 --> 00:53:56.360
You get excited about it, but you don't get access to it, right?

1480
00:53:56.360 --> 00:53:59.000
Well, believe it or not, the next blockbuster drug

1481
00:53:59.000 --> 00:54:00.440
that Lily is going to come out with,

1482
00:54:00.440 --> 00:54:01.920
probably in the next couple of months,

1483
00:54:01.920 --> 00:54:04.080
is this guy called Retotruthide, all right?

1484
00:54:04.080 --> 00:54:07.680
And Retotruthide is fantastic in that it is

1485
00:54:07.680 --> 00:54:11.520
the first three receptor agonist GLP1 drug.

1486
00:54:11.520 --> 00:54:13.240
So the GLP1 drugs, okay?

1487
00:54:13.240 --> 00:54:14.760
Whenever you're talking about

1488
00:54:14.760 --> 00:54:16.440
semi-glutide and transepetide,

1489
00:54:16.440 --> 00:54:17.680
they have slightly different profiles.

1490
00:54:17.680 --> 00:54:20.000
This is the Asimpyc category, correct, right?

1491
00:54:20.000 --> 00:54:23.520
So GLP1 is the primary receptor that they work on,

1492
00:54:23.520 --> 00:54:26.440
and what that will do is it slows gastric emptying

1493
00:54:26.440 --> 00:54:28.880
and it limits caloric intake, all right?

1494
00:54:28.880 --> 00:54:31.520
But then, and transepetide, not semi-glutide,

1495
00:54:31.520 --> 00:54:33.240
but transepetide is a dual agonist.

1496
00:54:33.240 --> 00:54:37.360
So it has a effect on GIP, which is a different receptor.

1497
00:54:37.360 --> 00:54:42.080
Well, Retotruthide adds in glucagon receptor activation.

1498
00:54:42.080 --> 00:54:44.800
And so believe it or not, your liver actually acts

1499
00:54:44.800 --> 00:54:46.440
like a repository of energy

1500
00:54:46.440 --> 00:54:49.000
where it stores glycogen and fat

1501
00:54:49.000 --> 00:54:50.680
that your body can use as energy.

1502
00:54:50.680 --> 00:54:51.880
But that's a problem, right?

1503
00:54:51.880 --> 00:54:52.920
If you get too much fat there,

1504
00:54:52.920 --> 00:54:54.560
if you have a caloric excess,

1505
00:54:54.560 --> 00:54:57.560
then you could end up having what's called NASH cirrhosis,

1506
00:54:57.560 --> 00:55:00.480
but non-alcoholic stato hepatitis,

1507
00:55:00.480 --> 00:55:01.760
basically inflammation of your liver

1508
00:55:01.760 --> 00:55:03.120
due to accumulating too much fat.

1509
00:55:03.120 --> 00:55:04.160
It's a problem.

1510
00:55:04.160 --> 00:55:07.000
But by stimulating the glucagon receptor

1511
00:55:07.000 --> 00:55:10.760
while simultaneously hitting GLP1 and GIP,

1512
00:55:10.760 --> 00:55:12.360
what we found is not only do patients lose

1513
00:55:12.360 --> 00:55:13.920
an incredible amount of weight,

1514
00:55:13.920 --> 00:55:16.200
but they also get the best improvements

1515
00:55:16.200 --> 00:55:18.680
we've ever seen in their liver health that we've ever seen.

1516
00:55:18.680 --> 00:55:21.120
And people have been buying that

1517
00:55:21.120 --> 00:55:23.560
from research use only websites

1518
00:55:23.560 --> 00:55:25.880
and using it for about two years now.

1519
00:55:25.880 --> 00:55:27.320
And bodybuilders have already made this

1520
00:55:27.320 --> 00:55:29.080
standard in their protocol when it comes to cutting

1521
00:55:29.080 --> 00:55:30.040
for a show.

1522
00:55:30.040 --> 00:55:32.760
And it is wildly effective.

1523
00:55:32.760 --> 00:55:35.880
And we're now seeing the population using a drug

1524
00:55:35.880 --> 00:55:38.240
at scale that hasn't even made it

1525
00:55:38.240 --> 00:55:40.920
through commercialization yet.

1526
00:55:40.920 --> 00:55:42.520
Oh, I used to not, can you, using it?

1527
00:55:42.520 --> 00:55:43.360
No.

1528
00:55:43.360 --> 00:55:44.720
I have not.

1529
00:55:44.720 --> 00:55:47.000
I can honestly say I have not used retta,

1530
00:55:47.000 --> 00:55:49.640
but I find it fascinating though.

1531
00:55:49.640 --> 00:55:50.800
It's absolutely wild.

1532
00:55:50.800 --> 00:55:53.400
Yeah, I'm talking about power to the people, right?

1533
00:55:53.400 --> 00:55:54.320
What about these others then?

1534
00:55:54.320 --> 00:55:56.000
What else have we got here that you think's interesting?

1535
00:55:56.000 --> 00:55:58.280
So we've got these two here

1536
00:55:58.280 --> 00:55:59.320
that I think are really interesting.

1537
00:55:59.320 --> 00:56:01.680
So CJC1295 and Ipa Moralim.

1538
00:56:01.680 --> 00:56:05.000
So the whole idea is that, can we stimulate growth hormone?

1539
00:56:05.000 --> 00:56:06.800
And there's an interesting story behind that.

1540
00:56:06.800 --> 00:56:09.280
Actually, growth hormone itself was very, very popular

1541
00:56:09.280 --> 00:56:11.760
for many, many years as an anti-aging compound.

1542
00:56:11.760 --> 00:56:14.640
But then we changed some laws here in the 1990, okay?

1543
00:56:14.640 --> 00:56:16.920
That made it a little dicey to prescribe growth hormone.

1544
00:56:16.920 --> 00:56:19.320
And also, it's kind of a blunt instrument.

1545
00:56:19.320 --> 00:56:21.280
We wanted something to stimulate more natural growth hormone

1546
00:56:21.280 --> 00:56:22.120
release.

1547
00:56:22.120 --> 00:56:23.360
So we have this entire class of medications

1548
00:56:23.360 --> 00:56:24.880
called secretedogs that help stimulate

1549
00:56:24.880 --> 00:56:26.360
natural growth hormone release.

1550
00:56:26.360 --> 00:56:27.880
And these are two of the most potent ones

1551
00:56:27.880 --> 00:56:29.360
that are often combined together.

1552
00:56:29.360 --> 00:56:31.720
And when we say growth hormone, yes.

1553
00:56:31.720 --> 00:56:33.280
What does growth hormone do?

1554
00:56:33.280 --> 00:56:35.640
So growth hormone acts like a signal

1555
00:56:35.640 --> 00:56:38.280
that tells your liver to make more of another compound

1556
00:56:38.280 --> 00:56:39.760
we talked about, IGF1.

1557
00:56:39.760 --> 00:56:42.200
What growth hormone does is growth hormone

1558
00:56:42.200 --> 00:56:44.480
actually stimulates building muscle, okay?

1559
00:56:44.480 --> 00:56:47.560
It also strips fat, okay?

1560
00:56:47.560 --> 00:56:50.640
And it's also been found to help with tissue healing.

1561
00:56:50.640 --> 00:56:51.480
Okay.

1562
00:56:51.480 --> 00:56:53.760
And so there's a significant benefit in that regard.

1563
00:56:53.760 --> 00:56:55.520
And so people want to boost their growth hormone,

1564
00:56:55.520 --> 00:56:57.880
improves quality of skin, improves quality of hair,

1565
00:56:57.880 --> 00:56:59.400
and nails, and that sort of thing.

1566
00:56:59.400 --> 00:57:03.680
And so these two compounds together are particularly potent.

1567
00:57:03.680 --> 00:57:08.680
CJC1295 being a growth hormone releasing hormone derivative.

1568
00:57:09.240 --> 00:57:14.040
And then we have Ipomoralin, which is a Grellen receptor agonist.

1569
00:57:14.040 --> 00:57:16.560
So again, release improving the release of growth hormone

1570
00:57:16.560 --> 00:57:18.800
through two different synergistic mechanisms.

1571
00:57:18.800 --> 00:57:20.720
And so that one is really, really interesting

1572
00:57:20.760 --> 00:57:22.000
or these two together.

1573
00:57:22.000 --> 00:57:25.760
And then on top of that, so this one, somatotropin,

1574
00:57:25.760 --> 00:57:27.240
another word for growth hormone, okay?

1575
00:57:27.240 --> 00:57:29.240
So this is growth hormone, okay?

1576
00:57:29.240 --> 00:57:30.640
Just a different word for it.

1577
00:57:30.640 --> 00:57:31.480
So what would happen?

1578
00:57:31.480 --> 00:57:32.320
Let's just take this one.

1579
00:57:32.320 --> 00:57:33.440
Somatotropin.

1580
00:57:33.440 --> 00:57:34.280
Yeah.

1581
00:57:34.280 --> 00:57:35.560
Somatotropin.

1582
00:57:35.560 --> 00:57:36.400
Yeah.

1583
00:57:36.400 --> 00:57:38.360
If I put this for research purposes,

1584
00:57:38.360 --> 00:57:39.400
my purpose is only.

1585
00:57:39.400 --> 00:57:41.880
And I started injecting some of this into me.

1586
00:57:41.880 --> 00:57:42.720
Yes.

1587
00:57:42.720 --> 00:57:43.560
What would change?

1588
00:57:43.560 --> 00:57:45.520
So it depends on how much you do and when you do it.

1589
00:57:45.520 --> 00:57:48.920
So the idea is that if you injected that at night,

1590
00:57:48.920 --> 00:57:50.960
you would improve your quality of sleep, okay?

1591
00:57:50.960 --> 00:57:54.280
You would get a boost in your quality of your hair,

1592
00:57:54.280 --> 00:57:56.760
your skin, nails, theoretically.

1593
00:57:56.760 --> 00:57:59.000
It would be easier for you to recover from injuries,

1594
00:57:59.000 --> 00:58:00.960
hopefully put on a little bit more muscle, a little bit easier,

1595
00:58:00.960 --> 00:58:02.240
maybe lose a little bit of fat.

1596
00:58:02.240 --> 00:58:03.320
So why didn't I take you?

1597
00:58:03.320 --> 00:58:04.880
Well, because if you take a little bit too much,

1598
00:58:04.880 --> 00:58:07.360
you can actually get insulin resistance

1599
00:58:07.360 --> 00:58:09.720
because your glucose levels will go too high for too long,

1600
00:58:09.720 --> 00:58:10.560
all right?

1601
00:58:10.560 --> 00:58:11.560
You'd use too much for too long.

1602
00:58:11.560 --> 00:58:12.920
You will actually get acromegaly.

1603
00:58:12.920 --> 00:58:16.760
So that's development of your bones continue to grow,

1604
00:58:16.760 --> 00:58:18.920
but not along only in certain junctures.

1605
00:58:18.920 --> 00:58:21.200
And so there's a very specific look that bodybuilders

1606
00:58:21.200 --> 00:58:23.800
who abuse growth hormone and high amounts will get to them,

1607
00:58:23.800 --> 00:58:25.520
all right, which is an irreversible change

1608
00:58:25.520 --> 00:58:26.880
to the facial bone structure.

1609
00:58:26.880 --> 00:58:29.280
You can also theoretically, if you had a cancer,

1610
00:58:29.280 --> 00:58:31.640
maybe it could make it worse, all right?

1611
00:58:31.640 --> 00:58:34.000
We've never shown it that it causes new cancers,

1612
00:58:34.000 --> 00:58:35.360
but that could be a concern.

1613
00:58:35.360 --> 00:58:37.640
And on top of that, it could give you insulin resistance

1614
00:58:37.640 --> 00:58:39.400
because you're again.

1615
00:58:39.400 --> 00:58:41.040
Yeah, exactly, right?

1616
00:58:41.040 --> 00:58:42.640
And if you take too much, it could potentially

1617
00:58:42.640 --> 00:58:43.880
make your hands numb in the morning

1618
00:58:43.880 --> 00:58:45.840
because you get effusions into the joint space.

1619
00:58:45.840 --> 00:58:48.360
And so bodybuilders will talk about lifting a dumbbell

1620
00:58:48.360 --> 00:58:50.280
and having to drop it because their hand goes numb temporarily

1621
00:58:50.280 --> 00:58:53.320
if they're taking too much growth hormone too soon.

1622
00:58:53.320 --> 00:58:54.400
And what else have we got here?

1623
00:58:54.400 --> 00:58:55.240
Oh my gosh.

1624
00:58:55.240 --> 00:58:56.400
So epithelan.

1625
00:58:56.400 --> 00:59:02.760
So this is the medication that is theoretically

1626
00:59:02.760 --> 00:59:06.080
going to be available to us in July, OK?

1627
00:59:06.080 --> 00:59:11.560
And so the hope is that this is going to expand cell life.

1628
00:59:11.560 --> 00:59:14.520
So epithelan, the purpose of it

1629
00:59:14.520 --> 00:59:18.760
is it works to enhance telomerase.

1630
00:59:18.760 --> 00:59:20.920
So at the end of your cells, imagine it this way.

1631
00:59:20.920 --> 00:59:22.680
You're trying to copy the genome,

1632
00:59:22.680 --> 00:59:26.080
but the little copier that copies it takes up

1633
00:59:26.080 --> 00:59:26.880
space enough itself.

1634
00:59:26.880 --> 00:59:28.400
So it's kind of like it cuts off the last couple

1635
00:59:28.400 --> 00:59:29.800
of letters every single time.

1636
00:59:29.800 --> 00:59:31.160
This is when you're aging.

1637
00:59:31.160 --> 00:59:33.120
When you're aging, you're creating new cells, right?

1638
00:59:33.120 --> 00:59:35.320
Cells divide through this process called mitosis,

1639
00:59:35.320 --> 00:59:36.680
where they split, all right?

1640
00:59:36.680 --> 00:59:38.360
Well, if you got to make an exact copy,

1641
00:59:38.360 --> 00:59:40.600
you've got to read through all these lines of code,

1642
00:59:40.640 --> 00:59:42.080
but because of the way that we're built,

1643
00:59:42.080 --> 00:59:44.640
we always end up cutting off the last little bit of code.

1644
00:59:44.640 --> 00:59:46.480
Now, which is how we age, which is how we age.

1645
00:59:46.480 --> 00:59:48.840
It is one of the things that contributes to aging, all right?

1646
00:59:48.840 --> 00:59:51.520
Now, that is considered to be, quote unquote,

1647
00:59:51.520 --> 00:59:52.560
junk information.

1648
00:59:52.560 --> 00:59:55.040
It's at the very end called the telomere, all right?

1649
00:59:55.040 --> 00:59:56.880
But we know that shorter telomeres

1650
00:59:56.880 --> 01:00:00.120
are associated with aging, potentially worse health outcomes.

1651
01:00:00.120 --> 01:00:03.000
And there is an enzyme that can help heal or repair

1652
01:00:03.000 --> 01:00:05.080
the telomere called telomerase.

1653
01:00:05.080 --> 01:00:07.280
Epithelan helps encourage that.

1654
01:00:07.280 --> 01:00:09.080
And so some people are looking at that

1655
01:00:09.120 --> 01:00:11.840
as being one of the fountain of youth compounds.

1656
01:00:11.840 --> 01:00:13.720
I'm very skeptical as far as that goes,

1657
01:00:13.720 --> 01:00:17.640
but it does show some benefits when it comes to healing parts

1658
01:00:17.640 --> 01:00:20.000
of your brain that are associated with regulating

1659
01:00:20.000 --> 01:00:21.080
your circadian rhythm.

1660
01:00:23.280 --> 01:00:25.000
So the average person listening now,

1661
01:00:25.000 --> 01:00:27.360
they've heard a lot of stuff about a lot of things.

1662
01:00:28.360 --> 01:00:31.840
How do they know if they should pursue

1663
01:00:31.840 --> 01:00:33.600
getting and taking peptides?

1664
01:00:33.600 --> 01:00:34.440
Like how do they know?

1665
01:00:34.440 --> 01:00:35.280
What are they looking for?

1666
01:00:35.280 --> 01:00:38.640
So what I will say is that think of peptides

1667
01:00:38.640 --> 01:00:40.600
as falling into three categories, all right?

1668
01:00:40.600 --> 01:00:42.480
You get category one, which are peptides

1669
01:00:42.480 --> 01:00:43.840
that you can prescribe right now,

1670
01:00:43.840 --> 01:00:45.760
legal from a commercial pharmacy.

1671
01:00:45.760 --> 01:00:49.360
That includes the GLP1's PT141, a Bremelanna tide.

1672
01:00:49.360 --> 01:00:51.640
I mentioned to you earlier, oxytocin is another one.

1673
01:00:51.640 --> 01:00:53.880
We have these different compounds that are available.

1674
01:00:53.880 --> 01:00:56.440
And then we have what we call category two.

1675
01:00:56.440 --> 01:00:58.000
If you don't have anything in right now,

1676
01:00:58.000 --> 01:01:00.800
but that will consist of the seven peptides

1677
01:01:00.800 --> 01:01:03.160
that are hopefully gonna be approved in July,

1678
01:01:03.160 --> 01:01:05.200
whenever they get moved from category two,

1679
01:01:05.200 --> 01:01:08.160
cannot compound, a category one can compound, all right?

1680
01:01:08.400 --> 01:01:10.880
And then everything else is kind of in this category three,

1681
01:01:10.880 --> 01:01:13.360
where it's only available for research use only.

1682
01:01:13.360 --> 01:01:15.480
And so my recommendation for patients is,

1683
01:01:15.480 --> 01:01:17.920
don't go out and buy research about use only compounds,

1684
01:01:17.920 --> 01:01:18.760
all right?

1685
01:01:18.760 --> 01:01:19.760
You don't know what you're getting,

1686
01:01:19.760 --> 01:01:21.240
and you don't know if you're dosing it right,

1687
01:01:21.240 --> 01:01:23.200
you don't know if it's contaminated.

1688
01:01:23.200 --> 01:01:24.800
So really what the public should be doing

1689
01:01:24.800 --> 01:01:26.480
is educating themselves on this,

1690
01:01:26.480 --> 01:01:28.560
and then going and talking to their doctors

1691
01:01:28.560 --> 01:01:30.360
about what problems they have,

1692
01:01:30.360 --> 01:01:33.720
and then potentially when those options become available,

1693
01:01:33.720 --> 01:01:36.920
a peptide might be part of the answer for their problem.

1694
01:01:36.920 --> 01:01:38.400
Okay, so speak to your doctor.

1695
01:01:38.400 --> 01:01:40.480
Yeah, consult with your doctor,

1696
01:01:40.480 --> 01:01:42.960
and make it a conversation with whoever your medical

1697
01:01:42.960 --> 01:01:44.760
professional is about your symptoms

1698
01:01:44.760 --> 01:01:45.760
and what might be useful,

1699
01:01:45.760 --> 01:01:48.720
and what the range, the toolbox, the options are,

1700
01:01:48.720 --> 01:01:50.240
correct, to attack those symptoms.

1701
01:01:50.240 --> 01:01:51.800
Yes, absolutely.

1702
01:01:51.800 --> 01:01:53.720
Talk, collaborate with your doctor.

1703
01:01:53.720 --> 01:01:54.880
Your doctor should be your partner

1704
01:01:54.880 --> 01:01:57.240
in you getting as healthy as humanly possible.

1705
01:01:58.200 --> 01:02:00.440
We talked about trizepa-tide,

1706
01:02:00.440 --> 01:02:01.920
Zempec, semi-glytide.

1707
01:02:01.920 --> 01:02:04.560
One of the questions that's fun to mind for everybody,

1708
01:02:04.560 --> 01:02:06.640
whether they're taking them or watching others take them,

1709
01:02:06.680 --> 01:02:08.560
is what happens when you stop?

1710
01:02:08.560 --> 01:02:09.400
We've looked at that.

1711
01:02:09.400 --> 01:02:10.560
You actually regain the weight.

1712
01:02:10.560 --> 01:02:12.120
And so, because the truth is,

1713
01:02:12.120 --> 01:02:15.480
is that you have introduced something into your life

1714
01:02:15.480 --> 01:02:17.640
that has moved the needle in one direction.

1715
01:02:17.640 --> 01:02:19.280
But if you don't change anything else,

1716
01:02:19.280 --> 01:02:20.560
well, you take that back out.

1717
01:02:20.560 --> 01:02:22.440
Well, you're gonna go back to where you were.

1718
01:02:22.440 --> 01:02:25.360
And so if you're going to maintain that weight loss,

1719
01:02:25.360 --> 01:02:28.040
you have to make lifestyle changes associated with that.

1720
01:02:28.040 --> 01:02:30.040
And what we found is that people do regain,

1721
01:02:30.040 --> 01:02:31.400
if they do make lifestyle changes,

1722
01:02:31.400 --> 01:02:32.920
they do regain some of the weight,

1723
01:02:32.920 --> 01:02:35.240
but not necessarily all of the weight.

1724
01:02:35.240 --> 01:02:38.280
And there's also data showing that you could potentially

1725
01:02:38.280 --> 01:02:40.880
stay on that medication, but at a much lower dose,

1726
01:02:40.880 --> 01:02:43.240
and then maintain your weight, okay?

1727
01:02:43.240 --> 01:02:45.120
So there are options to minimize

1728
01:02:45.120 --> 01:02:46.840
your medication burden long term.

1729
01:02:46.840 --> 01:02:48.560
And of all the things we've talked about today,

1730
01:02:48.560 --> 01:02:50.880
if you had to just pick one thing that excites you the most,

1731
01:02:50.880 --> 01:02:53.200
that's either coming down the pipe or here already.

1732
01:02:53.200 --> 01:02:54.040
Yeah.

1733
01:02:54.040 --> 01:02:54.880
What is the thing you're most excited about?

1734
01:02:54.880 --> 01:02:56.320
I see your eyes wondering.

1735
01:02:56.320 --> 01:02:58.840
Hands down, it's that one over there, a red or true tide.

1736
01:02:58.840 --> 01:03:03.040
Because the changes in body composition

1737
01:03:03.040 --> 01:03:06.160
that we have seen both in clinical trials, okay?

1738
01:03:06.160 --> 01:03:08.680
And in anecdotal reports from users

1739
01:03:08.680 --> 01:03:11.000
who have obtained on their own are wild.

1740
01:03:11.000 --> 01:03:15.600
We're talking losing 20 to 25% of total body weight

1741
01:03:15.600 --> 01:03:18.920
within a relatively short period of time.

1742
01:03:18.920 --> 01:03:23.160
And I think that this is going to be basically

1743
01:03:23.160 --> 01:03:26.400
the Ferrari of GLP1 medications when it comes out.

1744
01:03:26.400 --> 01:03:27.640
It's not for everybody, right?

1745
01:03:27.640 --> 01:03:29.760
It's gonna go faster than everything else,

1746
01:03:29.760 --> 01:03:31.520
but it's gonna change the game.

1747
01:03:31.520 --> 01:03:34.920
I think this is going to be a trillion dollar drug

1748
01:03:34.920 --> 01:03:36.120
when it comes out.

1749
01:03:36.120 --> 01:03:37.280
And no one's gonna ruin the patent

1750
01:03:37.280 --> 01:03:39.120
so everybody will be able to access it, is that right?

1751
01:03:39.120 --> 01:03:41.840
No, no, that is gonna belong solely to Lily.

1752
01:03:41.840 --> 01:03:43.440
And so you are going to see,

1753
01:03:43.440 --> 01:03:47.000
and they are going to enforce it as aggressively

1754
01:03:47.000 --> 01:03:48.640
as they've ever enforced anything.

1755
01:03:48.640 --> 01:03:52.160
But you will see profound results in patients.

1756
01:03:53.120 --> 01:03:55.120
People are referring to peptides

1757
01:03:55.120 --> 01:03:57.600
as Silicon Valley's miracle drug.

1758
01:03:57.600 --> 01:03:58.720
And I wondered why that was.

1759
01:03:58.720 --> 01:04:00.200
Why it's been associated with Silicon Valley?

1760
01:04:00.200 --> 01:04:01.200
Have you heard that at all?

1761
01:04:01.200 --> 01:04:02.680
I have, and I'll tell you,

1762
01:04:02.680 --> 01:04:07.680
I've seen some peptide stacks from Silicon Valley founders

1763
01:04:07.680 --> 01:04:11.880
and individuals that blow my mind.

1764
01:04:11.880 --> 01:04:13.760
I'm like, oh man, even I think that's a lot.

1765
01:04:13.760 --> 01:04:15.360
Why would people in Silicon Valley

1766
01:04:15.360 --> 01:04:17.440
why would founders be interested in peptides?

1767
01:04:17.440 --> 01:04:19.240
Well, I think it's because we all want to live

1768
01:04:19.240 --> 01:04:21.200
our best version of our own lives, right?

1769
01:04:21.200 --> 01:04:22.600
We want to perform at the highest level.

1770
01:04:22.600 --> 01:04:25.200
And so people will do whatever they can,

1771
01:04:25.200 --> 01:04:29.040
they'll drink caffeine, they'll pop a zen in their mouth

1772
01:04:29.040 --> 01:04:31.160
and they'll try to tweak whatever variable

1773
01:04:31.160 --> 01:04:33.480
they possibly can to get the best possible performance.

1774
01:04:33.480 --> 01:04:35.320
And the thing is, is that anabolic steroids

1775
01:04:35.320 --> 01:04:37.320
come with significant side effects,

1776
01:04:37.320 --> 01:04:39.040
and that's not everybody's cup of tea, right?

1777
01:04:39.040 --> 01:04:41.080
And the health consequences from high dose

1778
01:04:41.080 --> 01:04:43.680
androgens dwarf anything that you might experience

1779
01:04:43.680 --> 01:04:44.520
with peptides.

1780
01:04:44.520 --> 01:04:46.840
And so peptides offer a lot of flexibility

1781
01:04:46.840 --> 01:04:48.560
in pulling many different levers

1782
01:04:48.560 --> 01:04:51.560
that are interesting to your regular average person.

1783
01:04:51.560 --> 01:04:55.680
And honestly, it requires a little bit of DIY right now

1784
01:04:55.680 --> 01:04:57.400
because of the nature of these peptides.

1785
01:04:57.440 --> 01:05:01.640
And I think you combine that with the kind of rogue,

1786
01:05:01.640 --> 01:05:06.640
a founder spirit that is common in Silicon Valley.

1787
01:05:07.000 --> 01:05:08.640
And I think it's a perfect fit.

1788
01:05:08.640 --> 01:05:09.480
I asked you a second to go,

1789
01:05:09.480 --> 01:05:11.400
what are the three questions that people come to

1790
01:05:11.400 --> 01:05:13.160
and ask you as a doctor?

1791
01:05:13.160 --> 01:05:14.840
The first one as a related to peptides

1792
01:05:14.840 --> 01:05:16.720
was which peptides should it be taken?

1793
01:05:16.720 --> 01:05:18.040
Yeah, while there are any other questions

1794
01:05:18.040 --> 01:05:21.000
we haven't covered off that are commonplace in your practice.

1795
01:05:21.000 --> 01:05:23.920
The second one is, can you prescribe me?

1796
01:05:23.920 --> 01:05:26.360
And then I have to explain to them the regulatory environment,

1797
01:05:26.360 --> 01:05:28.640
surrounding peptides that as of right now,

1798
01:05:28.640 --> 01:05:30.000
the only peptides that I can prescribe

1799
01:05:30.000 --> 01:05:32.400
or the ones you can get from CVS or Walgreens,

1800
01:05:32.400 --> 01:05:34.440
which is going to be your GLP1 medications.

1801
01:05:34.440 --> 01:05:36.880
And a handful of others that usually aren't applying

1802
01:05:36.880 --> 01:05:39.520
to the young men that I see in my practice.

1803
01:05:39.520 --> 01:05:41.960
I've had so many founders speak to me and say,

1804
01:05:41.960 --> 01:05:43.560
why didn't this particular ad that I ran

1805
01:05:43.560 --> 01:05:45.560
on this platform work for me?

1806
01:05:45.560 --> 01:05:47.880
Maybe the copy wasn't good, the creative wasn't strong,

1807
01:05:47.880 --> 01:05:49.240
but usually the problem is they're not having

1808
01:05:49.240 --> 01:05:51.600
the right conversation because that ad never reached

1809
01:05:51.600 --> 01:05:52.600
the right person.

1810
01:05:52.600 --> 01:05:55.680
And if you're in B2B marketing, that is much of the game.

1811
01:05:55.680 --> 01:05:57.280
And this is where LinkedIn ads

1812
01:05:57.280 --> 01:05:59.160
solves that problem for you.

1813
01:05:59.160 --> 01:06:01.320
Their targeting is ridiculously specific.

1814
01:06:01.320 --> 01:06:02.960
You can target by job title,

1815
01:06:02.960 --> 01:06:05.320
seniority, company size, industry,

1816
01:06:05.320 --> 01:06:07.400
and even someone's skillset.

1817
01:06:07.400 --> 01:06:10.440
And then network includes over a billion professionals,

1818
01:06:10.440 --> 01:06:13.720
about 130 million of them are decision makers.

1819
01:06:13.720 --> 01:06:14.960
So when you use LinkedIn ads,

1820
01:06:14.960 --> 01:06:17.720
you're putting your brand in front of the right people.

1821
01:06:17.720 --> 01:06:20.080
And LinkedIn ads also drive the highest B2B return

1822
01:06:20.080 --> 01:06:23.120
on ad spend across all ad networks in my experience.

1823
01:06:23.120 --> 01:06:24.720
If you want to give them a try,

1824
01:06:24.760 --> 01:06:28.280
head over to LinkedIn.com slash diary.

1825
01:06:28.280 --> 01:06:31.880
And when you spend $250 on your first LinkedIn ads campaign,

1826
01:06:31.880 --> 01:06:36.520
you'll get an extra $250 credit from me for the next one.

1827
01:06:36.520 --> 01:06:40.360
That's LinkedIn.com slash diary, terms and conditions apply.

1828
01:06:41.440 --> 01:06:43.760
We have finally caved in.

1829
01:06:43.760 --> 01:06:46.560
So many of you have asked us if we could bundle

1830
01:06:46.560 --> 01:06:48.640
the conversation cards with the 1% diary.

1831
01:06:48.640 --> 01:06:50.120
For those of you that don't know,

1832
01:06:50.120 --> 01:06:52.320
every single time a guest sits here with me in the chair,

1833
01:06:52.320 --> 01:06:54.320
they leave a question in the diary of a CEO.

1834
01:06:54.320 --> 01:06:56.600
And then I ask that question to the next guest.

1835
01:06:56.600 --> 01:06:59.920
We don't release those questions in any environment other than

1836
01:06:59.920 --> 01:07:01.880
on these incredible conversation cards.

1837
01:07:01.880 --> 01:07:04.920
These have become a fantastic tool for people in relationships,

1838
01:07:04.920 --> 01:07:07.560
people in teams, in big corporations,

1839
01:07:07.560 --> 01:07:09.480
and also family members to connect with each other.

1840
01:07:09.480 --> 01:07:11.640
With that, we also have the 1% diary,

1841
01:07:11.640 --> 01:07:14.880
which is this incredible tool to change habits in your life.

1842
01:07:14.880 --> 01:07:16.560
So many of you have asked if it was possible

1843
01:07:16.560 --> 01:07:18.200
to buy both at the same time,

1844
01:07:18.200 --> 01:07:20.600
especially people in big companies.

1845
01:07:20.600 --> 01:07:23.440
So what we've done is we've bundled them together,

1846
01:07:23.440 --> 01:07:25.240
and you can buy both at the same time.

1847
01:07:25.240 --> 01:07:26.600
And if you want to drive connection

1848
01:07:26.600 --> 01:07:28.960
and then still habit change in your company,

1849
01:07:28.960 --> 01:07:30.800
head to the diary.com to inquire

1850
01:07:30.800 --> 01:07:32.160
and our team will be in touch.

1851
01:07:33.200 --> 01:07:36.000
Is there a super peptide for anti-aging and skin

1852
01:07:36.000 --> 01:07:37.240
and some of those issues?

1853
01:07:37.240 --> 01:07:38.840
Oh, for skin, GHKQ.

1854
01:07:38.840 --> 01:07:39.680
GHQ.

1855
01:07:39.680 --> 01:07:44.120
Yeah, so this is probably the most well-known peptide

1856
01:07:44.120 --> 01:07:46.880
for use for skin complexion.

1857
01:07:46.880 --> 01:07:49.960
And I mean, really, it may have some small benefits

1858
01:07:49.960 --> 01:07:51.120
when it comes to hair, all right,

1859
01:07:51.120 --> 01:07:53.560
but those reports are a little bit more spotty.

1860
01:07:53.560 --> 01:07:54.400
Is that okay?

1861
01:07:54.400 --> 01:07:55.240
Yeah.

1862
01:07:55.240 --> 01:07:56.600
And then outside of the world of peptides for a second,

1863
01:07:56.600 --> 01:08:00.000
yeah, I've got these three vials in my hand.

1864
01:08:00.000 --> 01:08:01.600
I'm so scared.

1865
01:08:01.600 --> 01:08:02.440
All right.

1866
01:08:04.440 --> 01:08:06.240
Do you know what those are?

1867
01:08:06.240 --> 01:08:08.400
Oh, yeah.

1868
01:08:08.400 --> 01:08:12.840
This is unfortunately our future for not careful.

1869
01:08:12.840 --> 01:08:13.680
Explain.

1870
01:08:13.680 --> 01:08:18.680
So what we've got here is we have three different canisters

1871
01:08:18.680 --> 01:08:22.760
containing water that has a little bit of coloring in it.

1872
01:08:22.760 --> 01:08:25.440
And what you can see is that all the way back in 1973,

1873
01:08:25.440 --> 01:08:27.400
this is pretty opaque, all right, like, you know,

1874
01:08:27.400 --> 01:08:30.320
this is not what you would, you can't see through it.

1875
01:08:30.320 --> 01:08:32.720
And then 2026 has a little bit of color to it.

1876
01:08:32.720 --> 01:08:37.080
And then we've got over here 2045, which is totally clear.

1877
01:08:37.080 --> 01:08:39.680
This unfortunately is actually representing

1878
01:08:39.680 --> 01:08:42.440
the fertility trajectory for young men.

1879
01:08:42.440 --> 01:08:46.600
Because what we're seeing is that back in 1973,

1880
01:08:46.600 --> 01:08:47.720
total modal sperm counts.

1881
01:08:47.720 --> 01:08:51.240
So how many healthy swimming sperm do we have in each ejaculation

1882
01:08:51.240 --> 01:08:55.440
is exponentially higher and more dense than what we're seeing today.

1883
01:08:55.440 --> 01:08:58.280
And so what we're seeing is a progressive decline

1884
01:08:58.280 --> 01:09:00.320
in male fertility over time.

1885
01:09:00.320 --> 01:09:02.000
And that's been demonstrated in multiple studies.

1886
01:09:02.000 --> 01:09:03.600
We've debated this at multiple meetings.

1887
01:09:03.600 --> 01:09:05.680
People tried to argue that it's a measuring difference.

1888
01:09:05.680 --> 01:09:09.040
But as we give it more time and as we give it more scrutiny,

1889
01:09:09.040 --> 01:09:09.800
this is real.

1890
01:09:09.800 --> 01:09:14.520
We are experiencing a significant decline in sperm quality

1891
01:09:14.520 --> 01:09:17.000
and motility and concentration.

1892
01:09:17.000 --> 01:09:18.400
Why?

1893
01:09:18.400 --> 01:09:22.760
So the leading culprits are going to be, yes,

1894
01:09:22.760 --> 01:09:25.360
microplastics and environmental toxins,

1895
01:09:25.360 --> 01:09:26.960
okay, things that are putting our environment

1896
01:09:26.960 --> 01:09:29.720
that we have been exposed to that we can't help.

1897
01:09:29.720 --> 01:09:32.680
But again, the biggest modifiable risk factor

1898
01:09:32.680 --> 01:09:35.320
is insulin resistance and metabolic disease.

1899
01:09:35.320 --> 01:09:36.160
obesity.

1900
01:09:36.160 --> 01:09:37.000
obesity.

1901
01:09:37.000 --> 01:09:40.720
And so a downstream effect that we may see

1902
01:09:40.720 --> 01:09:43.120
from peptides like we discussed before

1903
01:09:43.120 --> 01:09:45.600
is we may be able to help reverse this

1904
01:09:45.600 --> 01:09:47.680
for the first time in history by trying

1905
01:09:47.680 --> 01:09:50.040
to prevent the development of metabolic disease.

1906
01:09:50.040 --> 01:09:51.640
Using some of the peptides we talked about earlier.

1907
01:09:51.640 --> 01:09:53.360
Exactly, I'd give you the example of a patient

1908
01:09:53.360 --> 01:09:54.720
that I saw on clinic this past week

1909
01:09:54.720 --> 01:09:57.000
that increased his sperm count 10 times over.

1910
01:09:57.000 --> 01:09:59.000
Imagine if we had given that to him

1911
01:09:59.000 --> 01:10:00.440
before he even got that obese

1912
01:10:00.440 --> 01:10:02.120
when he just started to get a little bit overweight

1913
01:10:02.120 --> 01:10:03.360
and at a lower dose.

1914
01:10:03.360 --> 01:10:05.360
Well, he may have never ended up in my office, right?

1915
01:10:05.360 --> 01:10:07.200
Because his primary care doctor would have identified

1916
01:10:07.200 --> 01:10:08.040
that treated it.

1917
01:10:08.040 --> 01:10:10.040
And he never would have needed the specialist.

1918
01:10:10.040 --> 01:10:12.920
Hmm, it's crazy.

1919
01:10:12.920 --> 01:10:15.600
It's wild.

1920
01:10:15.600 --> 01:10:20.000
So ultimately, if you look at what are the ills

1921
01:10:20.000 --> 01:10:24.040
that are affecting health care in any first world nation,

1922
01:10:24.040 --> 01:10:27.120
the number one offender is metabolic disease

1923
01:10:27.120 --> 01:10:28.680
and metabolic dysfunction.

1924
01:10:28.680 --> 01:10:33.360
And this is something that was actually hinted at by RFK

1925
01:10:33.360 --> 01:10:37.600
whenever he was talking about root cause of disease.

1926
01:10:37.600 --> 01:10:39.680
Well, yes, we have many, many diseases

1927
01:10:39.680 --> 01:10:42.080
and many, many infections that don't stem necessarily

1928
01:10:42.080 --> 01:10:43.240
from insulin resistance.

1929
01:10:43.240 --> 01:10:44.640
But if we look at cardiac disease,

1930
01:10:44.640 --> 01:10:48.240
if we look at issues with lack of perfusion,

1931
01:10:48.240 --> 01:10:50.600
my specialty, erectile dysfunction, right?

1932
01:10:50.600 --> 01:10:51.520
We look at cancer.

1933
01:10:51.520 --> 01:10:53.840
All of this is related back to obesity

1934
01:10:53.840 --> 01:10:55.120
and metabolic dysfunction.

1935
01:10:55.120 --> 01:10:58.280
And so if we can eliminate that as a society

1936
01:10:58.280 --> 01:11:00.800
or we can minimize it to as little as possible,

1937
01:11:00.800 --> 01:11:04.240
well, I mean, man, maybe I'd finally work myself out of a job.

1938
01:11:04.240 --> 01:11:06.120
Your speciality is erectile dysfunction.

1939
01:11:06.120 --> 01:11:09.840
Yeah, so my specialty is this branch off of urology

1940
01:11:09.840 --> 01:11:11.960
that we broadly call men's health, okay?

1941
01:11:11.960 --> 01:11:13.840
And so what that incorporates for us

1942
01:11:13.840 --> 01:11:16.800
is going to be low testosterone, advanced hormone management.

1943
01:11:16.800 --> 01:11:18.280
I take that a little bit for the most people.

1944
01:11:18.280 --> 01:11:19.320
That's totally cool.

1945
01:11:19.320 --> 01:11:22.040
And then also a erectile dysfunction,

1946
01:11:22.040 --> 01:11:23.520
peronis disease, which is damaged

1947
01:11:23.520 --> 01:11:25.240
to the penis that causes curvature.

1948
01:11:25.240 --> 01:11:28.440
And then male fertility on top of that.

1949
01:11:28.440 --> 01:11:30.800
And I do a little other thing,

1950
01:11:30.800 --> 01:11:33.520
treating leaky-gefter prostate cancer treatment.

1951
01:11:33.520 --> 01:11:34.880
And that's basically it.

1952
01:11:34.880 --> 01:11:38.880
I treat like five things maybe and that's it.

1953
01:11:38.880 --> 01:11:42.120
So I'm very, very specialized because I was the kid

1954
01:11:42.120 --> 01:11:43.760
that I like to take my sandwiches apart

1955
01:11:43.760 --> 01:11:44.760
and eat it one at a time.

1956
01:11:44.760 --> 01:11:46.000
I was very precise.

1957
01:11:46.000 --> 01:11:46.840
And I figured, you know,

1958
01:11:46.840 --> 01:11:49.040
you can do a lot of things in this world and be okay at them.

1959
01:11:49.040 --> 01:11:50.680
Or you can pick like, I don't know, four or five

1960
01:11:50.680 --> 01:11:51.800
and get pretty good at them.

1961
01:11:51.800 --> 01:11:54.320
So that seemed to work for me.

1962
01:11:54.320 --> 01:11:56.640
I was looking at a photo of you five years ago

1963
01:11:56.640 --> 01:11:57.920
and you were very different.

1964
01:11:57.920 --> 01:11:58.760
Yeah.

1965
01:11:58.760 --> 01:11:59.960
You've changed a lot.

1966
01:11:59.960 --> 01:12:05.480
So I will tell you this.

1967
01:12:05.760 --> 01:12:10.760
Medical training in the United States has gotten better,

1968
01:12:13.640 --> 01:12:15.280
but it is grueling.

1969
01:12:15.280 --> 01:12:16.800
It's absolutely grueling.

1970
01:12:17.840 --> 01:12:19.800
For five years,

1971
01:12:19.800 --> 01:12:23.440
I worked anywhere from 80 to 100 hours a week in a hospital.

1972
01:12:24.400 --> 01:12:27.200
No eating, very little sleep.

1973
01:12:27.200 --> 01:12:28.920
Did not care for yourself at all.

1974
01:12:30.240 --> 01:12:31.920
And again, we can argue whether or not

1975
01:12:31.920 --> 01:12:33.960
that's necessary all day long.

1976
01:12:34.000 --> 01:12:38.160
But the truth is is that it really beat me down.

1977
01:12:38.160 --> 01:12:43.160
It absolutely took me apart physically and psychologically.

1978
01:12:43.400 --> 01:12:45.080
In part, it's designed to do that

1979
01:12:45.080 --> 01:12:46.840
because the idea is that as a surgeon,

1980
01:12:46.840 --> 01:12:49.120
you have to be able to perform

1981
01:12:49.120 --> 01:12:51.160
when all the lights are on,

1982
01:12:51.160 --> 01:12:52.680
when everything is against you,

1983
01:12:52.680 --> 01:12:54.960
you have to be the one holding together in the operating room

1984
01:12:54.960 --> 01:12:57.120
and command that ship and save that patient.

1985
01:12:58.080 --> 01:13:01.880
And I remember being totally devastated

1986
01:13:01.880 --> 01:13:03.560
towards the end of training.

1987
01:13:03.560 --> 01:13:08.560
And I did a very challenging surgery on a very needy patient.

1988
01:13:08.600 --> 01:13:11.000
Gentlemen was about to go into renal failure,

1989
01:13:11.000 --> 01:13:12.600
did not have a lot of kidney left.

1990
01:13:12.600 --> 01:13:16.080
And he had a very challenging kidney tumor

1991
01:13:16.080 --> 01:13:18.440
that was in a very treacherous location.

1992
01:13:18.440 --> 01:13:21.440
It was in a location where he should have lost that kidney

1993
01:13:21.440 --> 01:13:24.680
by all measure if we were gonna take out that cancer.

1994
01:13:24.680 --> 01:13:26.960
And he was at a county hospital.

1995
01:13:26.960 --> 01:13:29.240
He had no insurance,

1996
01:13:29.240 --> 01:13:32.120
and we swung for the fences

1997
01:13:32.120 --> 01:13:35.040
and did a very, very challenging operation on him.

1998
01:13:35.040 --> 01:13:39.240
And against our best efforts with having everybody there,

1999
01:13:39.240 --> 01:13:43.160
he ended up having a bleed postoperatively that night.

2000
01:13:43.160 --> 01:13:44.480
And I remember getting the call.

2001
01:13:44.480 --> 01:13:48.320
I was on call and that he is blood pressure had dropped

2002
01:13:48.320 --> 01:13:49.440
and that he did not look well.

2003
01:13:49.440 --> 01:13:50.800
And I knew exactly what it was

2004
01:13:50.800 --> 01:13:53.560
because again, this was a very treacherous surgery.

2005
01:13:53.560 --> 01:13:56.360
And I went in in the middle of the night with my attending,

2006
01:13:56.360 --> 01:13:57.280
who was a different attending

2007
01:13:57.280 --> 01:13:59.320
the one I did the initial surgery with.

2008
01:13:59.320 --> 01:14:02.240
And I remember just opening him up

2009
01:14:03.520 --> 01:14:06.960
and just being covered in blood

2010
01:14:06.960 --> 01:14:08.920
that we were taking out of the abdominal field

2011
01:14:08.920 --> 01:14:10.440
that we were evacuating,

2012
01:14:10.440 --> 01:14:12.680
eventually identifying the area of the bleed.

2013
01:14:12.680 --> 01:14:15.160
And there was no way that it could have been avoided.

2014
01:14:15.160 --> 01:14:16.560
I remember my attending yelling at me

2015
01:14:16.560 --> 01:14:19.480
and we ultimately had to take that guy's kidney.

2016
01:14:19.480 --> 01:14:24.400
And I remember walking out of there,

2017
01:14:24.400 --> 01:14:26.640
just being totally shattered, covered in blood,

2018
01:14:26.640 --> 01:14:28.560
crying on a hallway by myself.

2019
01:14:28.560 --> 01:14:31.640
Wondering if, what was the point?

2020
01:14:31.640 --> 01:14:33.640
Like, is there a tomorrow after this?

2021
01:14:33.640 --> 01:14:34.960
Like, I spent all this time in this training,

2022
01:14:34.960 --> 01:14:35.880
like, am I good enough?

2023
01:14:35.880 --> 01:14:37.920
Am I gonna be able to make this?

2024
01:14:37.920 --> 01:14:42.320
And I wasn't well put together, wasn't healthy.

2025
01:14:42.320 --> 01:14:45.360
And I ended up spending a lot of time in that patient,

2026
01:14:45.360 --> 01:14:46.760
literally held his hand throughout

2027
01:14:46.760 --> 01:14:48.400
the rest of his hospital stay.

2028
01:14:48.400 --> 01:14:52.360
And he ended up recovering and against all odds.

2029
01:14:52.360 --> 01:14:56.920
But afterwards, I took a strong interest

2030
01:14:56.920 --> 01:15:00.480
in not only taking care of my patients,

2031
01:15:00.480 --> 01:15:05.040
but also practicing what I preach, taking care of myself

2032
01:15:05.040 --> 01:15:07.000
and prioritizing my own health.

2033
01:15:07.000 --> 01:15:07.840
I got evaluated.

2034
01:15:07.840 --> 01:15:10.120
I was diagnosed with low testosterone myself.

2035
01:15:10.120 --> 01:15:11.760
Turns out not eating or sleeping for five years

2036
01:15:11.760 --> 01:15:12.760
to do a number on you.

2037
01:15:12.760 --> 01:15:14.640
I can't lose his old stress.

2038
01:15:14.640 --> 01:15:16.720
Through the roof, 24-7.

2039
01:15:16.720 --> 01:15:19.480
I cannot even imagine what, you know,

2040
01:15:19.480 --> 01:15:22.120
there's a part in the brain called the hippocampus

2041
01:15:22.120 --> 01:15:25.560
that they, when they do MRIs on soldiers

2042
01:15:25.560 --> 01:15:26.640
that come back from war.

2043
01:15:26.680 --> 01:15:28.720
That'll be degenerated in them.

2044
01:15:28.720 --> 01:15:31.040
I wonder if we did that in surgical trainees,

2045
01:15:31.040 --> 01:15:32.360
what that would look like.

2046
01:15:32.360 --> 01:15:37.160
But I made a commitment to take care of my patients,

2047
01:15:37.160 --> 01:15:39.880
to take care of myself and make that a priority.

2048
01:15:39.880 --> 01:15:43.680
And to be simultaneously the best doctor

2049
01:15:43.680 --> 01:15:46.760
and the best father and husband that I could be.

2050
01:15:46.760 --> 01:15:49.120
Not perfect, made a lot of mistakes along the way.

2051
01:15:49.120 --> 01:15:51.760
But what you're seeing from five years ago

2052
01:15:51.760 --> 01:15:54.240
is where I was, I've been in training after seven years,

2053
01:15:54.240 --> 01:15:56.440
so it took a while to kind of recover from that.

2054
01:15:56.440 --> 01:15:58.520
What you're seeing is, you know,

2055
01:15:58.520 --> 01:15:59.920
what focusing on health and wellness

2056
01:15:59.920 --> 01:16:01.120
can potentially look like.

2057
01:16:02.680 --> 01:16:06.240
The emotion in you is palpable when you talk about this.

2058
01:16:06.240 --> 01:16:08.760
And I'm wondering where that comes from.

2059
01:16:08.760 --> 01:16:09.840
What is it, because you're looking off

2060
01:16:09.840 --> 01:16:11.520
into the distance at something.

2061
01:16:12.520 --> 01:16:13.720
And I don't know what you're looking at.

2062
01:16:13.720 --> 01:16:15.360
Yeah, I mean,

2063
01:16:20.320 --> 01:16:22.600
when I'm caring for my patients

2064
01:16:22.600 --> 01:16:26.320
and I see a young man that is struggling

2065
01:16:26.320 --> 01:16:27.400
with his fertility,

2066
01:16:27.400 --> 01:16:29.200
and he wants to be a father.

2067
01:16:30.720 --> 01:16:32.240
I was that guy.

2068
01:16:32.240 --> 01:16:35.000
Me and my wife couldn't get pregnant when we first tried.

2069
01:16:35.000 --> 01:16:35.880
We ended up having to do

2070
01:16:35.880 --> 01:16:38.120
in vitro fertilization at IVF.

2071
01:16:38.120 --> 01:16:40.280
I remember feeling like I wasn't a man

2072
01:16:40.280 --> 01:16:42.760
because I was sitting in that room holding her hand

2073
01:16:42.760 --> 01:16:45.520
and not having any answers to why things weren't working.

2074
01:16:46.560 --> 01:16:49.480
When I see my patients who come in that are,

2075
01:16:49.480 --> 01:16:52.120
you know, struggling because their hormones are out of whack

2076
01:16:52.120 --> 01:16:54.120
and no matter how they try to take care of themselves,

2077
01:16:54.120 --> 01:16:55.520
something just isn't clicking.

2078
01:16:56.440 --> 01:16:58.160
I've been that guy.

2079
01:16:58.160 --> 01:17:00.480
And then when I see my other patients

2080
01:17:00.480 --> 01:17:02.320
that are further on in life and struggling with things

2081
01:17:02.320 --> 01:17:05.400
like prostate cancer or rectal essential for the case,

2082
01:17:05.400 --> 01:17:09.720
maybe I see my father, my uncle, my grandfather,

2083
01:17:09.720 --> 01:17:11.400
like these,

2084
01:17:11.400 --> 01:17:14.600
but and they are someone's father, grandfather and uncle.

2085
01:17:14.600 --> 01:17:15.640
Like these are our brothers.

2086
01:17:15.640 --> 01:17:18.960
And this is who I have been called to care for.

2087
01:17:18.960 --> 01:17:21.520
And I care for my patients deeply.

2088
01:17:21.520 --> 01:17:24.200
And it's because I care for my patients.

2089
01:17:24.200 --> 01:17:26.840
And like this is a calling for me

2090
01:17:26.840 --> 01:17:28.560
that I care about stuff like this

2091
01:17:28.560 --> 01:17:32.440
because I want my patients to have every tool physically possible

2092
01:17:32.440 --> 01:17:34.080
to live their best quality alive

2093
01:17:34.080 --> 01:17:36.400
so that they can be whole and they can be happy

2094
01:17:36.400 --> 01:17:39.520
and so that they can be the best version of themselves

2095
01:17:39.520 --> 01:17:40.920
for their loved ones.

2096
01:17:47.440 --> 01:17:50.440
Well, thank you for caring because it matters.

2097
01:17:50.440 --> 01:17:53.360
And a lot of this stuff is quite opaque

2098
01:17:53.360 --> 01:17:55.200
and confusing to an average person like me.

2099
01:17:55.200 --> 01:17:57.000
But I'm so glad that we have people

2100
01:17:57.000 --> 01:17:58.080
there in the world like you

2101
01:17:58.080 --> 01:18:00.080
that are demystifying all of this for us

2102
01:18:00.080 --> 01:18:01.680
and explaining it in simple terms,

2103
01:18:01.680 --> 01:18:04.400
but also championing it because one of the things

2104
01:18:04.400 --> 01:18:05.400
I've learned from me in this podcast

2105
01:18:05.400 --> 01:18:08.160
is solutions to problems that a lot of people are suffering

2106
01:18:08.160 --> 01:18:09.800
where they're auctioned right in front of us,

2107
01:18:09.800 --> 01:18:11.440
but they need voices and educators

2108
01:18:11.440 --> 01:18:14.240
like yourself out there leading the charge

2109
01:18:14.240 --> 01:18:15.960
so that these types of things are available

2110
01:18:15.960 --> 01:18:17.760
to everyone, not just the few.

2111
01:18:17.760 --> 01:18:19.400
Absolutely, not just the billionaires

2112
01:18:19.400 --> 01:18:21.920
you can get whatever they want straight away any day.

2113
01:18:21.920 --> 01:18:26.920
Yeah, I mean, you know, it's a one thing I love is that

2114
01:18:27.600 --> 01:18:29.080
I've been very blessed in my practice

2115
01:18:29.080 --> 01:18:31.480
to take care of people that are much fancier than I am

2116
01:18:31.480 --> 01:18:33.440
and sit in boardrooms and that sort of thing.

2117
01:18:33.440 --> 01:18:34.760
But you know what?

2118
01:18:34.760 --> 01:18:38.480
I love taking care of my regular patients

2119
01:18:38.480 --> 01:18:41.760
who are, you know, farmers, iron workers, you know,

2120
01:18:41.760 --> 01:18:43.800
tradesmen, guys that, you know,

2121
01:18:43.800 --> 01:18:46.920
truthfully I have more in common with than anyone else.

2122
01:18:46.920 --> 01:18:47.960
You know, I joke with my patients,

2123
01:18:47.960 --> 01:18:49.320
I'm just an over educated plumber

2124
01:18:49.320 --> 01:18:51.160
at the end of the day, right, urologist.

2125
01:18:51.160 --> 01:18:55.440
And so it's a health is for everyone,

2126
01:18:55.440 --> 01:18:57.440
not just for the fortunate.

2127
01:18:57.440 --> 01:18:58.960
The last thing I wanted to talk to you about

2128
01:18:58.960 --> 01:19:00.440
is linked but random.

2129
01:19:00.440 --> 01:19:03.720
Yes, it's the enhanced games.

2130
01:19:03.720 --> 01:19:05.000
Let's do it.

2131
01:19:05.000 --> 01:19:07.920
I am so excited about these.

2132
01:19:07.920 --> 01:19:09.160
So do you know them?

2133
01:19:09.160 --> 01:19:10.280
I do very well.

2134
01:19:10.280 --> 01:19:14.480
So for those of you or for those who may not know,

2135
01:19:14.480 --> 01:19:17.240
the enhanced games is a project

2136
01:19:17.240 --> 01:19:20.840
based off of the world anti-doping agencies own data,

2137
01:19:20.840 --> 01:19:22.840
potentially up to 40% of athletes

2138
01:19:22.840 --> 01:19:24.600
that are competing at the Olympic level,

2139
01:19:24.600 --> 01:19:26.200
you have either are currently using

2140
01:19:26.200 --> 01:19:29.720
or have used band substances at some point in time, right?

2141
01:19:29.720 --> 01:19:32.200
And also, we know that a lot of the compounds

2142
01:19:32.200 --> 01:19:33.960
that are used for enhancement

2143
01:19:33.960 --> 01:19:35.800
maybe aren't quite so dangerous

2144
01:19:35.800 --> 01:19:37.080
if they're being administered

2145
01:19:37.080 --> 01:19:39.640
by a trained medical professional with proper oversight.

2146
01:19:39.640 --> 01:19:41.600
And as of right now, that's not happening.

2147
01:19:41.600 --> 01:19:45.440
Also, at the same time, we know that Olympic athletes

2148
01:19:45.440 --> 01:19:46.640
aren't paid enough, right?

2149
01:19:46.640 --> 01:19:48.280
These are the best of the best of the best

2150
01:19:48.280 --> 01:19:51.160
and they're not even making the poverty line a lot of years.

2151
01:19:51.160 --> 01:19:53.600
And so the idea is this, well, what if we go ahead

2152
01:19:53.600 --> 01:19:55.720
and we strip away those rules, okay?

2153
01:19:55.720 --> 01:19:57.640
We allow athletes to use medications

2154
01:19:57.640 --> 01:19:58.840
that can enhance performance.

2155
01:19:58.840 --> 01:20:00.440
We watch them very closely

2156
01:20:00.440 --> 01:20:01.800
and we have a team of doctors

2157
01:20:01.800 --> 01:20:03.960
and medical professionals watching them.

2158
01:20:03.960 --> 01:20:07.080
And then let's see what they can do

2159
01:20:07.080 --> 01:20:08.640
at these traditional Olympic events

2160
01:20:08.640 --> 01:20:10.640
and see if they smash world records.

2161
01:20:10.640 --> 01:20:12.800
Oh, and they're gonna give 250 grand

2162
01:20:12.800 --> 01:20:14.120
to any first place winners

2163
01:20:14.120 --> 01:20:17.520
and a million dollars to anyone that hits a world record.

2164
01:20:17.520 --> 01:20:19.240
And just for comparison,

2165
01:20:19.240 --> 01:20:21.200
how much are Olympic athletes getting paid?

2166
01:20:21.200 --> 01:20:23.320
They don't get paid to compete at all, okay?

2167
01:20:23.320 --> 01:20:25.520
So they don't get paid to be an Olympic athlete.

2168
01:20:25.520 --> 01:20:27.880
They end up getting sponsorship deals

2169
01:20:27.880 --> 01:20:30.240
and that's potentially the money that they can make.

2170
01:20:30.240 --> 01:20:31.640
So yeah.

2171
01:20:31.640 --> 01:20:32.640
Interesting.

2172
01:20:32.640 --> 01:20:34.200
So it's basically the doping Olympics

2173
01:20:34.200 --> 01:20:35.560
where everyone's allowed to dope.

2174
01:20:35.560 --> 01:20:36.400
That's the idea.

2175
01:20:36.400 --> 01:20:37.640
There are some caveats in there

2176
01:20:37.640 --> 01:20:40.440
they're trying to say that only FDA approved medications

2177
01:20:40.440 --> 01:20:41.280
can be used, okay?

2178
01:20:41.280 --> 01:20:43.000
So you couldn't use something like trend alone,

2179
01:20:43.000 --> 01:20:45.720
which is for veterinary use only

2180
01:20:45.720 --> 01:20:47.360
or theoretically any of the compounds

2181
01:20:47.360 --> 01:20:48.080
we've talked about today

2182
01:20:48.080 --> 01:20:49.400
because they're not FDA approved.

2183
01:20:49.400 --> 01:20:50.680
But also at the same time,

2184
01:20:50.680 --> 01:20:52.360
they've said that they're not gonna test for those things

2185
01:20:52.360 --> 01:20:54.600
and one of their athletes,

2186
01:20:54.600 --> 01:20:57.640
Magnuson has openly admitted taking BPC 157

2187
01:20:57.640 --> 01:20:58.480
and that's where things.

2188
01:20:58.480 --> 01:21:00.320
So I think we can kind of figure out

2189
01:21:00.320 --> 01:21:03.520
that it may just be a wide open playing field maybe.

2190
01:21:03.520 --> 01:21:06.440
So the International Olympic Committee

2191
01:21:06.440 --> 01:21:08.480
does not pay athletes a single cent

2192
01:21:08.480 --> 01:21:10.240
for winning a gold medal.

2193
01:21:10.240 --> 01:21:11.680
Yep, just crazy.

2194
01:21:11.680 --> 01:21:13.520
How many billions do you think they make off of those?

2195
01:21:13.520 --> 01:21:14.560
Well, they'll advertise them.

2196
01:21:14.560 --> 01:21:15.920
So much money.

2197
01:21:15.920 --> 01:21:17.000
Right.

2198
01:21:17.000 --> 01:21:17.840
Yeah.

2199
01:21:17.840 --> 01:21:20.040
And this is taking place in Las Vegas

2200
01:21:20.040 --> 01:21:22.640
May 21st through the 24th, I believe.

2201
01:21:22.640 --> 01:21:23.800
Are you gonna go?

2202
01:21:23.800 --> 01:21:25.600
I'm gonna be watching, that's for sure.

2203
01:21:25.600 --> 01:21:26.600
Do you wanna go?

2204
01:21:26.600 --> 01:21:27.720
I would love to go.

2205
01:21:27.720 --> 01:21:29.440
That would be incredible.

2206
01:21:29.440 --> 01:21:30.280
Well, if you wanna go,

2207
01:21:30.280 --> 01:21:32.760
I know a few people that are putting the event on

2208
01:21:32.760 --> 01:21:34.200
so do let me know.

2209
01:21:34.200 --> 01:21:35.720
I'm there, I'm already interested.

2210
01:21:35.720 --> 01:21:37.280
You got my attention.

2211
01:21:37.280 --> 01:21:39.000
Is there anything else we should have talked about

2212
01:21:39.000 --> 01:21:39.840
that we didn't talk about

2213
01:21:39.840 --> 01:21:42.200
as it relates to this subject we've discussed today?

2214
01:21:42.200 --> 01:21:44.480
I mean, honestly, I think that we've gone pretty deep

2215
01:21:44.480 --> 01:21:45.440
on peptides.

2216
01:21:45.440 --> 01:21:49.440
And so I think we've covered that.

2217
01:21:49.440 --> 01:21:53.760
But one thing that I did want to just leave with you

2218
01:21:53.760 --> 01:21:54.840
because I think it's pretty humorous.

2219
01:21:54.840 --> 01:21:56.440
And I think you've talked to some of my colleagues

2220
01:21:56.440 --> 01:21:57.560
about this before.

2221
01:21:57.560 --> 01:22:00.400
But one of the things that I deal with as a surgical specialist

2222
01:22:00.400 --> 01:22:02.200
is the end stage of Vascular disease,

2223
01:22:02.200 --> 01:22:03.560
the end stage of diabetes,

2224
01:22:03.560 --> 01:22:06.440
which is going to be erectile dysfunction, all right?

2225
01:22:06.440 --> 01:22:08.360
And believe it or not,

2226
01:22:08.360 --> 01:22:10.760
whenever we're dealing with that in male patients,

2227
01:22:10.760 --> 01:22:12.120
they eventually get to a point where things like

2228
01:22:12.120 --> 01:22:14.520
viagran, Cialis, do not work, all right?

2229
01:22:14.520 --> 01:22:17.080
And that is a dark place to be as a guy.

2230
01:22:17.080 --> 01:22:18.680
And so you're taking these medications,

2231
01:22:18.680 --> 01:22:20.720
all you're getting is a headache and nothing else.

2232
01:22:20.720 --> 01:22:22.880
And then maybe you have other options.

2233
01:22:22.880 --> 01:22:25.480
They're actually injections you can do in the penis,

2234
01:22:25.480 --> 01:22:27.800
which is about as appetizing as you might imagine.

2235
01:22:27.800 --> 01:22:29.800
But men want a better solution.

2236
01:22:29.800 --> 01:22:33.040
And they'll come to us as sexual medicine specialists

2237
01:22:33.040 --> 01:22:35.120
you know, seeking that and that's what I do.

2238
01:22:35.120 --> 01:22:37.120
So the bulk of my surgical practice

2239
01:22:37.120 --> 01:22:39.320
is actually fixing a erectile dysfunction

2240
01:22:39.320 --> 01:22:41.560
with a procedure called implant placement, okay?

2241
01:22:41.560 --> 01:22:42.400
Oh, no.

2242
01:22:42.400 --> 01:22:43.240
Absolutely.

2243
01:22:43.240 --> 01:22:46.800
So now, I think did Reena show you one of these last time?

2244
01:22:46.800 --> 01:22:48.440
She brought it and I didn't ask it.

2245
01:22:48.440 --> 01:22:49.280
You didn't.

2246
01:22:49.280 --> 01:22:51.480
It makes me like, I get full body shudders

2247
01:22:51.480 --> 01:22:52.320
when I talk about this stuff.

2248
01:22:52.320 --> 01:22:54.720
Yeah, the thought of putting that up my penis.

2249
01:22:54.720 --> 01:22:55.880
Well, so you couldn't show me.

2250
01:22:55.880 --> 01:22:56.720
No, you couldn't show me.

2251
01:22:56.720 --> 01:22:58.480
Well, I would tell you, the good news is you don't have to.

2252
01:22:58.480 --> 01:23:01.320
Okay, like that's what we have a job for, okay?

2253
01:23:01.320 --> 01:23:03.280
But the way I explain to patients is like this.

2254
01:23:03.280 --> 01:23:05.960
So take this out of the picture, okay?

2255
01:23:05.960 --> 01:23:07.720
Ultimately, like the male erection

2256
01:23:07.720 --> 01:23:10.400
is just two inflatable tubes that start in the pelvis

2257
01:23:10.400 --> 01:23:11.520
and go out the shaft of the penis.

2258
01:23:11.520 --> 01:23:12.720
It makes sense, right?

2259
01:23:12.720 --> 01:23:14.880
It is a hydraulic motion.

2260
01:23:14.880 --> 01:23:15.800
What happens is you get stimulated,

2261
01:23:15.800 --> 01:23:17.520
get a rush of blood into those tubes,

2262
01:23:17.520 --> 01:23:19.720
get a rigid erection, able to use that for intimacy.

2263
01:23:19.720 --> 01:23:20.680
And then when you climax,

2264
01:23:20.680 --> 01:23:23.320
pop off valve opens back up and everything drains out, all right?

2265
01:23:23.320 --> 01:23:24.640
So if you can understand brakes on a car,

2266
01:23:24.640 --> 01:23:25.880
you can understand erections.

2267
01:23:25.880 --> 01:23:28.560
But the problem is that when you have long-term metabolic

2268
01:23:28.560 --> 01:23:31.040
and vascular dysfunction, the brake lines,

2269
01:23:31.040 --> 01:23:33.320
the blood vessels that feed those erections, they fail.

2270
01:23:33.320 --> 01:23:35.560
And all of a sudden you can't get enough blood flow

2271
01:23:35.560 --> 01:23:37.480
for it to work and believe it or not,

2272
01:23:37.480 --> 01:23:39.560
you can actually get atrophy of the penis over time

2273
01:23:39.560 --> 01:23:41.320
and you actually lose size, all right?

2274
01:23:41.320 --> 01:23:44.200
Which no man is eager to see, all right?

2275
01:23:44.200 --> 01:23:47.480
But whenever the easy things, like oral medications,

2276
01:23:47.480 --> 01:23:49.520
viagrancy, I also don't work anymore,

2277
01:23:49.520 --> 01:23:51.280
the next best option if we're looking

2278
01:23:51.280 --> 01:23:54.120
at patient satisfaction, durability, concealability,

2279
01:23:54.120 --> 01:23:56.360
is this little thing that I do,

2280
01:23:56.360 --> 01:24:00.400
which is what if we took our own tubes, okay?

2281
01:24:00.400 --> 01:24:02.600
And we put them inside your body's natural ones.

2282
01:24:02.600 --> 01:24:04.600
It's invisible, nobody looking at you could ever tell

2283
01:24:04.640 --> 01:24:06.280
that you've ever had anything done.

2284
01:24:06.280 --> 01:24:08.120
But all of a sudden, when you want to get erections,

2285
01:24:08.120 --> 01:24:09.920
stemmed to rely on pills that don't work

2286
01:24:09.920 --> 01:24:11.680
or putting a needle in there, right?

2287
01:24:11.680 --> 01:24:13.800
You could reach down and there's a small pump

2288
01:24:13.800 --> 01:24:16.160
that we hide underneath the skin down in the scrotum.

2289
01:24:16.160 --> 01:24:17.880
Okay, so I joke, it's like a third testicle,

2290
01:24:17.880 --> 01:24:20.160
but again, nothing external, nothing you can see.

2291
01:24:20.160 --> 01:24:22.360
And all of a sudden, whenever you squeeze this,

2292
01:24:22.360 --> 01:24:24.760
what it does is it moves saline that we hide

2293
01:24:24.760 --> 01:24:26.760
and a little reservoir that goes in the belly.

2294
01:24:26.760 --> 01:24:29.040
You never feel that into the cylinders.

2295
01:24:29.040 --> 01:24:32.240
And all of a sudden, men are able to get a firm,

2296
01:24:32.240 --> 01:24:35.800
rigid erection that looks natural, feels natural.

2297
01:24:35.800 --> 01:24:37.280
And they can use it as long as they want

2298
01:24:37.280 --> 01:24:39.560
or until they're partner sick of them.

2299
01:24:39.560 --> 01:24:41.360
And then press the button and it goes back down.

2300
01:24:41.360 --> 01:24:43.320
Do they still feel the same pleasure?

2301
01:24:43.320 --> 01:24:45.440
Yeah, so it does not affect sensation.

2302
01:24:45.440 --> 01:24:47.760
And so the nerves that affect sensation

2303
01:24:47.760 --> 01:24:49.800
run along the top of the penis.

2304
01:24:49.800 --> 01:24:52.360
If you're looking at a clock at the 12 o'clock position,

2305
01:24:52.360 --> 01:24:54.960
and we stay totally away from those.

2306
01:24:54.960 --> 01:24:58.680
So this is surgically put inside the penis.

2307
01:24:58.680 --> 01:24:59.800
All internal.

2308
01:24:59.800 --> 01:25:02.680
And believe it or not, that takes me about 13 minutes to do.

2309
01:25:02.680 --> 01:25:04.200
How many people have these?

2310
01:25:04.200 --> 01:25:07.640
Well, I've put in about 11 or 1200 personally,

2311
01:25:07.640 --> 01:25:08.480
but...

2312
01:25:08.480 --> 01:25:09.320
I live in a 12 hundred.

2313
01:25:09.320 --> 01:25:10.160
Yeah, yeah.

2314
01:25:10.160 --> 01:25:11.000
This is quite a lot of people.

2315
01:25:11.000 --> 01:25:12.360
There'll be people listening now that have these.

2316
01:25:12.360 --> 01:25:13.760
Well, you know, this is what's interesting.

2317
01:25:13.760 --> 01:25:15.960
If you look at in the United States right now,

2318
01:25:15.960 --> 01:25:18.680
okay, there are 30 million men with erectile dysfunction

2319
01:25:18.680 --> 01:25:19.680
in the United States right now.

2320
01:25:19.680 --> 01:25:22.400
That's more than the population of Australia, all right?

2321
01:25:22.400 --> 01:25:23.240
Oh, wow.

2322
01:25:23.240 --> 01:25:25.840
And if you look at statistics, the oral medications

2323
01:25:25.840 --> 01:25:28.080
are gonna fail in 15 to 40% of those men,

2324
01:25:28.080 --> 01:25:29.560
the first time they fail that.

2325
01:25:29.560 --> 01:25:31.600
And so you're talking about millions and millions of men

2326
01:25:31.600 --> 01:25:33.720
who aren't responding to oral medications

2327
01:25:33.720 --> 01:25:35.120
and need a better option.

2328
01:25:35.120 --> 01:25:37.400
So what is the button to get rid of the erection?

2329
01:25:37.400 --> 01:25:38.640
You see those two little bars right there?

2330
01:25:38.640 --> 01:25:39.480
These two.

2331
01:25:39.480 --> 01:25:40.880
Yeah, go ahead and put your thumb on it.

2332
01:25:40.880 --> 01:25:42.120
I, yep, do that.

2333
01:25:42.120 --> 01:25:44.840
And then squeeze from the end of the device

2334
01:25:44.840 --> 01:25:46.480
back towards the pump.

2335
01:25:46.480 --> 01:25:47.400
So squeeze the squeeze.

2336
01:25:47.400 --> 01:25:48.840
Yep, right there.

2337
01:25:48.840 --> 01:25:49.680
There you go.

2338
01:25:49.680 --> 01:25:50.520
It's down.

2339
01:25:52.440 --> 01:25:54.240
And then you would have the weight of your natural tissue

2340
01:25:54.240 --> 01:25:55.880
push things down.

2341
01:25:55.880 --> 01:25:57.400
Okay, and then yeah, okay.

2342
01:25:57.400 --> 01:25:58.480
There you go.

2343
01:25:58.480 --> 01:25:59.320
Okay.

2344
01:25:59.720 --> 01:26:00.560
Okay.

2345
01:26:00.560 --> 01:26:02.360
Well, you know, I'm happy people have the options

2346
01:26:02.360 --> 01:26:04.640
because I can imagine what that would be like

2347
01:26:04.640 --> 01:26:05.640
to not be able to get an erection.

2348
01:26:05.640 --> 01:26:06.960
It would be devastating, frankly.

2349
01:26:06.960 --> 01:26:07.880
Well, I'll tell you this.

2350
01:26:07.880 --> 01:26:09.200
I get more hugs and high fives

2351
01:26:09.200 --> 01:26:10.680
than anybody else in my practice.

2352
01:26:10.680 --> 01:26:12.240
And that includes the guys that treat kidney stones

2353
01:26:12.240 --> 01:26:13.080
and cancer.

2354
01:26:13.080 --> 01:26:15.640
So I feel like doing some good work here

2355
01:26:15.640 --> 01:26:17.600
until peptides put me out of business.

2356
01:26:17.600 --> 01:26:19.960
I don't think that's gonna happen anytime soon.

2357
01:26:19.960 --> 01:26:21.400
And you have a great YouTube channel.

2358
01:26:21.400 --> 01:26:22.400
Thank you, I appreciate that.

2359
01:26:22.400 --> 01:26:23.800
Which I think everybody should go check out

2360
01:26:23.800 --> 01:26:25.520
because you really are great at explaining

2361
01:26:25.520 --> 01:26:26.520
all this stuff in simple terms.

2362
01:26:26.520 --> 01:26:30.280
So I'm gonna link Dr. Alex's YouTube channel down below.

2363
01:26:30.280 --> 01:26:31.120
We'll try and collab.

2364
01:26:31.120 --> 01:26:33.920
So if you just click on the Diodevisio icon now,

2365
01:26:33.920 --> 01:26:35.400
you'll see Alex's channel.

2366
01:26:35.400 --> 01:26:37.160
And I highly recommend you go check out his content

2367
01:26:37.160 --> 01:26:38.680
because he's really leading the charge

2368
01:26:38.680 --> 01:26:39.680
on the subject of peptides.

2369
01:26:39.680 --> 01:26:41.280
When I spoke to my team,

2370
01:26:41.280 --> 01:26:43.200
and said I wanna have a conversation about peptides,

2371
01:26:43.200 --> 01:26:44.200
they gave me lots of options

2372
01:26:44.200 --> 01:26:46.240
of lots of different types of doctors.

2373
01:26:46.240 --> 01:26:48.920
And you were by far and away our preference

2374
01:26:48.920 --> 01:26:50.720
because of the very fact that you're very, very good

2375
01:26:50.720 --> 01:26:51.960
at communicating, you understand people.

2376
01:26:51.960 --> 01:26:53.360
And as you've demonstrated today,

2377
01:26:53.360 --> 01:26:54.640
you have a very big heart.

2378
01:26:54.640 --> 01:26:55.480
I appreciate that.

2379
01:26:55.480 --> 01:26:58.720
Clearly it was wonderful to see what's actually driving you.

2380
01:26:58.720 --> 01:26:59.560
And you did that in a way,

2381
01:26:59.560 --> 01:27:02.400
which is irrefutably authentic.

2382
01:27:02.400 --> 01:27:05.000
So please go check out Alex's channel.

2383
01:27:05.000 --> 01:27:06.800
He's around your own 100,000 subscribers

2384
01:27:06.800 --> 01:27:08.120
on that channel now?

2385
01:27:08.120 --> 01:27:10.960
So close, we're at like 98.99, any minute now.

2386
01:27:10.960 --> 01:27:13.040
Okay, so hopefully we can help push you over

2387
01:27:14.280 --> 01:27:17.360
that milestone.

2388
01:27:17.360 --> 01:27:18.200
Yeah.

2389
01:27:18.200 --> 01:27:20.000
We have a closing traditional Alex on this podcast

2390
01:27:20.000 --> 01:27:21.480
where the last guest leaves a question for the next.

2391
01:27:21.480 --> 01:27:22.680
Not knowing who they're leaving it for.

2392
01:27:22.680 --> 01:27:23.520
Okay.

2393
01:27:23.520 --> 01:27:25.400
The question left for you is,

2394
01:27:25.400 --> 01:27:30.040
if you could give $1 billion to one person,

2395
01:27:30.040 --> 01:27:32.400
you don't know personally.

2396
01:27:32.400 --> 01:27:36.160
Who is it and what do they have to spend it on?

2397
01:27:40.720 --> 01:27:45.720
Honestly, I would give it to Elon Musk, okay?

2398
01:27:46.040 --> 01:27:49.560
And it's not because I think that he's hurting

2399
01:27:49.560 --> 01:27:51.160
for a billion dollars right now.

2400
01:27:51.200 --> 01:27:55.320
But if you look at what he is working on

2401
01:27:55.320 --> 01:27:58.960
to accomplish for us as a human race, right?

2402
01:27:58.960 --> 01:28:01.760
He, I truly believe from what I've seen

2403
01:28:01.760 --> 01:28:03.880
that he has a similar heart for humanity

2404
01:28:03.880 --> 01:28:05.680
that I've seen in a lot of physicians.

2405
01:28:05.680 --> 01:28:09.640
But on a macro scale as an engineer and an entrepreneur,

2406
01:28:09.640 --> 01:28:11.480
he's trying to solve some of the greatest problems

2407
01:28:11.480 --> 01:28:13.080
that are facing us today.

2408
01:28:13.080 --> 01:28:15.720
And I think that what we are going to see,

2409
01:28:15.720 --> 01:28:19.920
hopefully coming from the Terra Fab down in Austin

2410
01:28:19.920 --> 01:28:23.840
is going to be wild with recursive feedback and engineering

2411
01:28:23.840 --> 01:28:25.880
on AI chips that are going to get better

2412
01:28:25.880 --> 01:28:27.840
and better and better in a short period of time.

2413
01:28:27.840 --> 01:28:32.000
And increasing independence when it comes to chip foundries

2414
01:28:32.000 --> 01:28:34.920
for the United States, it's wild.

2415
01:28:34.920 --> 01:28:38.920
And I think that that billion dollars would go further

2416
01:28:38.920 --> 01:28:42.400
and do more for more people than anywhere else I could put it.

2417
01:28:42.400 --> 01:28:43.520
And he's also working on Neuralink,

2418
01:28:43.520 --> 01:28:44.480
which is a really interesting company,

2419
01:28:44.480 --> 01:28:47.200
which puts a sort of brain chip interfaces

2420
01:28:47.200 --> 01:28:51.120
with our people to here again, see again,

2421
01:28:51.120 --> 01:28:53.480
allow paraplegics to walk again,

2422
01:28:53.480 --> 01:28:55.640
which is really, really incredible.

2423
01:28:55.640 --> 01:28:57.240
Dr. Alex, thank you so much.

2424
01:28:57.240 --> 01:28:58.080
It's so limiting.

2425
01:28:58.080 --> 01:28:59.600
I can't wait to have you back again some time soon

2426
01:28:59.600 --> 01:29:01.880
to talk about all the other things we could have talked about today.

2427
01:29:01.880 --> 01:29:03.280
We focused on peptides predominantly,

2428
01:29:03.280 --> 01:29:04.800
but I know that over on YouTube channel

2429
01:29:04.800 --> 01:29:06.200
you talk about a lot more than that.

2430
01:29:06.200 --> 01:29:08.880
So highly recommend everybody go check out Dr. Alex's YouTube channel.

2431
01:29:08.880 --> 01:29:09.960
And it's been a pleasure.

2432
01:29:09.960 --> 01:29:10.800
Thank you.

2433
01:29:10.800 --> 01:29:11.800
Thank you, Stephen.
